Molecular Mechanisms of Desensitization in the Iris

Honkanen, Richard E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Eye Institute (NEI)
• Type: Postdoctoral Individual National Research Service Award (F32)
• Project #: 7F32EY006050-03
• Application #: 3039021
• Study Section: Vision Research and Training Committee (VSN)
• Project Start: 1987-06-01
• Project End: 1990-06-01
• Budget Start: 1989-09-01
• Budget End: 1989-12-31
• Support Year: 3
• Fiscal Year: 1988

Institution

• Name: University of Hawaii
• Type: Organized Research Units
• DUNS #: 121911077
• City: Honolulu
• State: HI
• Country: United States
• Zip Code: 96822

Publications

Honkanen, R E; Dukelow, M; Zwiller, J et al. (1991) Cyanobacterial nodularin is a potent inhibitor of type 1 and type 2A protein phosphatases. Mol Pharmacol 40:577-83

Honkanen, R E; Howard, E F; Abdel-Latif, A A (1990) M3-muscarinic receptor subtype predominates in the bovine iris sphincter smooth muscle and ciliary processes. Invest Ophthalmol Vis Sci 31:590-3

Honkanen, R E; Abdel-Latif, A A (1989) Muscarinic-agonist and guanine nucleotide stimulation of myo-inositol trisphosphate formation in membranes isolated from bovine iris sphincter smooth muscle: effects of short-term cholinergic desensitization. Membr Biochem 8:39-59

Honkanen, R E; Abdel-Latif, A A (1988) Characterization of cholinergic muscarinic receptors in the rabbit iris. Biochem Pharmacol 37:2575-83

Honkanen, R E; Abdel-Latif, A A (1988) AFDX-116 discriminates between muscarinic M2 receptors of the heart and the iris smooth muscle. Mol Cell Biochem 82:131-5