Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Academic/Teacher Award (ATA) (K07)
Project #
5K07HL003437-02
Application #
2027073
Study Section
Special Emphasis Panel (ZHL1-CSR-Y (M1))
Project Start
1995-09-15
Project End
2000-07-31
Budget Start
1996-09-25
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Surgery
Type
Schools of Medicine
DUNS #
605799469
City
Newark
State
NJ
Country
United States
Zip Code
07107
Aramoto, Haruo; Breslin, Jerome W; Pappas, Peter J et al. (2004) Vascular endothelial growth factor stimulates differential signaling pathways in in vivo microcirculation. Am J Physiol Heart Circ Physiol 287:H1590-8
Breslin, Jerome W; Pappas, Peter J; Cerveira, Joaquim J et al. (2003) VEGF increases endothelial permeability by separate signaling pathways involving ERK-1/2 and nitric oxide. Am J Physiol Heart Circ Physiol 284:H92-H100
Varma, Shubha; Breslin, Jerome W; Lal, Brajesh K et al. (2002) p42/44MAPK regulates baseline permeability and cGMP-induced hyperpermeability in endothelial cells. Microvasc Res 63:172-8
Saito, S; Trovato, M J; You, R et al. (2001) Role of matrix metalloproteinases 1, 2, and 9 and tissue inhibitor of matrix metalloproteinase-1 in chronic venous insufficiency. J Vasc Surg 34:930-8
Lal, B K; Varma, S; Pappas, P J et al. (2001) VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways. Microvasc Res 62:252-62
Kissin, M; Kansal, N; Pappas, P J et al. (2000) Vein interposition cuffs decrease the intimal hyperplastic response of polytetrafluoroethylene bypass grafts. J Vasc Surg 31:69-83
Hanna, A K; Duran, W N; Leconte, I et al. (2000) Adenoviral-mediated expression of antisense RNA to basic fibroblast growth factor reduces tangential stress in arterialized vein grafts. J Vasc Surg 31:770-80
Kansal, N; Pappas, P J; Gwertzman, G A et al. (1999) Patency and limb salvage for polytetrafluoroethylene bypasses with vein interposition cuffs. Ann Vasc Surg 13:386-92
Padberg Jr, F T; Maniker, A H; Carmel, G et al. (1999) Sensory impairment: a feature of chronic venous insufficiency. J Vasc Surg 30:836-42
Pappas, P J; You, R; Rameshwar, P et al. (1999) Dermal tissue fibrosis in patients with chronic venous insufficiency is associated with increased transforming growth factor-beta1 gene expression and protein production. J Vasc Surg 30:1129-45

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