The aims of this project are to correlate changes in SOD levels with a particular disease, namely ARDS and to assess the effectiveness of the SOD variants at alleviating the damage in a rat model of acute lung injury. This project will also address the mechanisms of extracellular superoxide dismutase alterations in mammalian tissue culture models of oxidative stress and identify possible markers of acute lung injury in vivo.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Minority School Faculty Development Awards (K14)
Project #
5K14HL003157-02
Application #
2211240
Study Section
Special Emphasis Panel (ZHL1-CCT-L (F1))
Project Start
1994-05-13
Project End
1996-08-31
Budget Start
1995-09-01
Budget End
1996-08-31
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Miscellaneous
Type
Other Domestic Higher Education
DUNS #
015634884
City
Aurora
State
CO
Country
United States
Zip Code
80045