In patients with type I diabetes, the impact of hypoinsulinemia, hyperglycemia, and increased plasma fatty acids on myocardial perfusion, intermediary metabolism and mechanical function, at rest and during pharmacological stress will be assessed. Measurements of myocardial perfusion and metabolism will be obtained by PET and measurements of myocardial mechanical function will be measured by MRI.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
2M01RR000036-40
Application #
6412772
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
1974-10-01
Project End
2003-11-30
Budget Start
Budget End
Support Year
40
Fiscal Year
2000
Total Cost
Indirect Cost
Name
Washington University
Department
Type
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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Obermeit, Lisa C; Beltran, Jessica; Casaletto, Kaitlin B et al. (2017) Evaluating the accuracy of self-report for the diagnosis of HIV-associated neurocognitive disorder (HAND): defining ""symptomatic"" versus ""asymptomatic"" HAND. J Neurovirol 23:67-78

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