Correlate Immune Protection in AIDS Vaccine Recipients

Wolinsky, Steven M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research and Development Contracts (N01)
• Project #: N01AI045218-004
• Application #: 2296144
• Project Start: 1994-06-30
• Project End: 1999-06-29
• Budget Start: 1996-06-26
• Budget End: 1997-06-29
• Fiscal Year: 1996

Institution

• Name: Northwestern University at Chicago
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 005436803
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60611

Publications

Binley, J M; Jin, X; Huang, Y et al. (1998) Persistent antibody responses but declining cytotoxic T-lymphocyte responses to multiple human immunodeficiency virus type 1 antigens in a long-term nonprogressing individual with a defective p17 proviral sequence and no detectable viral RNA expression. J Virol 72:3472-4

Paxton, W A; Koup, R A (1997) Mechanisms of resistance to HIV infection. Springer Semin Immunopathol 18:323-40

Perelson, A S; Neumann, A U; Markowitz, M et al. (1996) HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 271:1582-6

Klasse, P J; Moore, J P (1996) Quantitative model of antibody- and soluble CD4-mediated neutralization of primary isolates and T-cell line-adapted strains of human immunodeficiency virus type 1. J Virol 70:3668-77

Moore, J P; Trkola, A; Korber, B et al. (1995) A human monoclonal antibody to a complex epitope in the V3 region of gp120 of human immunodeficiency virus type 1 has broad reactivity within and outside clade B. J Virol 69:122-30