Animal Models for Antiviral Evaluation

Soike, Kenneth F.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research and Development Contracts (N01)
• Project #: N01AI062521-005
• Application #: 2296514
• Project Start: 1986-02-10
• Project End: 1991-02-09
• Budget Start: 1988-11-23
• Budget End: 1990-02-09
• Fiscal Year: 1989

Institution

• Name: Tulane University
• Type: Primate Centers
• City: New Orleans
• State: LA
• Country: United States
• Zip Code: 70118

Publications

Soike, K F; Bohm, R; Huang, J L et al. (1993) Efficacy of (-)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine in African green monkeys infected with simian varicella virus. Antimicrob Agents Chemother 37:1370-2

Soike, K F; Huang, J L; Zhang, J Y et al. (1991) Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys. Antiviral Res 16:17-28

Soike, K F; Chou, T C; Fox, J J et al. (1990) Inhibition of simian varicella virus infection of monkeys by 1-(2-deoxy-2- fluoro-1-beta-D-arabinofuranosyl)-5-ethyluracil (FEAU) and synergistic effects of combination with human recombinant interferon-beta. Antiviral Res 13:165-74

Soike, K F; Eppstein, D A; Gloff, C A et al. (1987) Effect of 9-(1,3-dihydroxy-2-propoxymethyl)guanine and recombinant human beta interferon alone and in combination on simian varicella virus infection in monkeys. J Infect Dis 156:607-14