Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG002901-05
Application #
3114578
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1980-09-01
Project End
1987-08-31
Budget Start
1985-09-01
Budget End
1986-08-31
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Boise VA Medical Center
Department
Type
DUNS #
City
Boise
State
ID
Country
United States
Zip Code
83702
Vestal, R E; Cusack, B J; Crowley, J J et al. (1993) Aging and the response to inhibition and induction of theophylline metabolism. Exp Gerontol 28:421-33
Nielson, C P; Vestal, R E (1989) Effects of adenosine on polymorphonuclear leucocyte function, cyclic 3': 5'-adenosine monophosphate, and intracellular calcium. Br J Pharmacol 97:882-8
Loi, C M; Day, J D; Jue, S G et al. (1989) Dose-dependent inhibition of theophylline metabolism by disulfiram in recovering alcoholics. Clin Pharmacol Ther 45:476-86
Morgan, M E; Vestal, R E (1989) Methylxanthine effects on caudate dopamine release as measured by in vivo electrochemistry. Life Sci 45:2025-39
Crowley, J J; Cusack, B J; Jue, S G et al. (1988) Aging and drug interactions. II. Effect of phenytoin and smoking on the oxidation of theophylline and cortisol in healthy men. J Pharmacol Exp Ther 245:513-23
Cusack, B J; Tesnohlidek, D A; Loseke, V L et al. (1988) Effect of phenytoin on the pharmacokinetics of doxorubicin and doxorubicinol in the rabbit. Cancer Chemother Pharmacol 22:294-8
Nielson, C P; Crowley, J J; Morgan, M E et al. (1988) Polymorphonuclear leukocyte inhibition by therapeutic concentrations of theophylline is mediated by cyclic-3',5'-adenosine monophosphate. Am Rev Respir Dis 137:25-30
Crowley, J J; Cusack, B J; Jue, S G et al. (1987) Cigarette smoking and theophylline metabolism: effects of phenytoin. Clin Pharmacol Ther 42:334-40
Jenne, J W; Shaughnessy, T K; Druz, W S et al. (1987) In vivo functional antagonism between isoproterenol and bronchoconstrictants in the dog. J Appl Physiol 63:812-9
Vestal, R E; Cusack, B J; Mercer, G D et al. (1987) Aging and drug interactions. I. Effect of cimetidine and smoking on the oxidation of theophylline and cortisol in healthy men. J Pharmacol Exp Ther 241:488-500

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