Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032764-02
Application #
3147891
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1991-09-01
Project End
1993-01-31
Budget Start
1992-09-01
Budget End
1993-01-31
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Woulfe, S L; Bono, C P; Zacheis, M L et al. (1997) A peptidomimetic that specifically inhibits human leukocyte antigen DRB1*0401-restricted T cell proliferation. J Pharmacol Exp Ther 281:663-9
Fu, X T; Bono, C P; Woulfe, S L et al. (1995) Pocket 4 of the HLA-DR(alpha,beta 1*0401) molecule is a major determinant of T cells recognition of peptide. J Exp Med 181:915-26
Kirschmann, D A; Duffin, K L; Smith, C E et al. (1995) Naturally processed peptides from rheumatoid arthritis associated and non-associated HLA-DR alleles. J Immunol 155:5655-62
Woulfe, S L; Bono, C P; Zacheis, M L et al. (1995) Negatively charged residues interacting with the p4 pocket confer binding specificity to DRB1*0401. Arthritis Rheum 38:1744-53
Nygard, N R; Giacoletto, K S; Bono, C et al. (1994) Peptide binding to surface class II molecules is the major pathway of formation of immunogenic class II-peptide complexes for viable antigen presenting cells. J Immunol 152:1082-93
Nygard, N R; Schwartz, B D (1993) Infection and autoimmunity. Adv Intern Med 38:337-59