Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI036450-02
Application #
2072748
Study Section
Virology Study Section (VR)
Project Start
1995-09-30
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Genetics
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Krause, Christopher D; Izotova, Lara S; Pestka, Sidney (2013) Analytical use of multi-protein Fluorescence Resonance Energy Transfer to demonstrate membrane-facilitated interactions within cytokine receptor complexes. Cytokine 64:298-309
Krause, Christopher D; Digioia, Gina; Izotova, Lara S et al. (2013) Improving the spectral analysis of Fluorescence Resonance Energy Transfer in live cells: application to interferon receptors and Janus kinases. Cytokine 64:272-85
Krause, Christopher D; Digioia, Gina; Izotova, Lara S et al. (2013) Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity. Cytokine 64:286-97
Walberg, Kristin; Baron, Samuel; Poast, Joyce et al. (2008) Interferon protects mice against inhalation anthrax. J Interferon Cytokine Res 28:597-601
Krause, Christopher D; Pestka, Sidney (2007) Historical developments in the research of interferon receptors. Cytokine Growth Factor Rev 18:473-82
Qu, Yongxia; Adler, Victor; Izotova, Lara et al. (2007) The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type--but not by oncogenic--ras-p21 protein. Front Biosci 12:5089-97
Krause, Christopher D; Yang, Zhi-Hong; Kim, Young-Sun et al. (2007) Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential. Pharmacol Ther 113:50-87
Pestka, Sidney (2007) The interferons: 50 years after their discovery, there is much more to learn. J Biol Chem 282:20047-51
Krause, Christopher D; Mei, Erwen; Mirochnitchenko, Olga et al. (2006) Interactions among the components of the interleukin-10 receptor complex. Biochem Biophys Res Commun 340:377-85
Qu, Yongxia; Adler, Victor; Chu, Tearina et al. (2006) Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes. Front Biosci 11:2420-7

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