Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037075-02
Application #
2073668
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1995-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dartmouth College
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Miga, A J; Masters, S R; Durell, B G et al. (2001) Dendritic cell longevity and T cell persistence is controlled by CD154-CD40 interactions. Eur J Immunol 31:959-65
Becher, B; Durell, B G; Miga, A V et al. (2001) The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system. J Exp Med 193:967-74
Howard, L M; Miga, A J; Vanderlugt, C L et al. (1999) Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. J Clin Invest 103:281-90
Buhlmann, J E; Gonzalez, M; Ginther, B et al. (1999) Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease. J Immunol 162:4373-6
Gonzalez, M; Mackay, F; Browning, J L et al. (1998) The sequential role of lymphotoxin and B cells in the development of splenic follicles. J Exp Med 187:997-1007
Mackey, M F; Gunn, J R; Maliszewsky, C et al. (1998) Dendritic cells require maturation via CD40 to generate protective antitumor immunity. J Immunol 161:2094-8
Mackey, M F; Gunn, J R; Ting, P P et al. (1997) Protective immunity induced by tumor vaccines requires interaction between CD40 and its ligand, CD154. Cancer Res 57:2569-74