Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI052663-02
Application #
6690373
Study Section
AIDS and Related Research 8 (AARR)
Program Officer
Gupta, Kailash C
Project Start
2002-12-15
Project End
2005-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$487,178
Indirect Cost
Name
University of Washington
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Kraft, John C; McConnachie, Lisa A; Koehn, Josefin et al. (2018) Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation. J Control Release 275:229-241
Freeling, Jennifer P; Koehn, Josefin; Shu, Cuiling et al. (2014) Long-acting three-drug combination anti-HIV nanoparticles enhance drug exposure in primate plasma and cells within lymph nodes and blood. AIDS 28:2625-7
Endsley, Aaron N; Ho, Rodney J Y (2012) Elucidation of the time course of adenosine deaminase APOBEC3G and viral infectivity factor vif in HIV-2(287) -infected infant macaques. J Med Primatol 41:52-9
Crouthamel, Matthew H; Kelly, Edward J; Ho, Rodney J Y (2012) Development and characterization of transgenic mouse models for conditional gene knockout in the blood-brain and blood-CSF barriers. Transgenic Res 21:113-30
Ho, Rodney J Y; Chien, Jenny Y (2012) Drug delivery trends in clinical trials and translational medicine: growth in biologic molecule development and impact on rheumatoid arthritis, Crohn's disease, and colitis. J Pharm Sci 101:2668-74
Endsley, Aaron N; Ho, Rodney J Y (2012) Enhanced anti-HIV efficacy of indinavir after inclusion in CD4-targeted lipid nanoparticles. J Acquir Immune Defic Syndr 61:417-24
Chien, Jenny Y; Ho, Rodney J Y (2011) Drug delivery trends in clinical trials and translational medicine: evaluation of pharmacokinetic properties in special populations. J Pharm Sci 100:53-8
Ho, Martin T; Kelly, Edward J; Bodor, Miklos et al. (2011) Novel cytochrome P450-2D6 promoter sequence variations in hepatitis C positive and negative subjects. Ann Hepatol 10:327-32
Ho, Rodney J Y (2011) Editorial: human genome information. J Pharm Sci 100:4045-6
Ho, Beatrice E; Shen, Danny D; McCune, Jeannine S et al. (2010) Effects of Garlic on Cytochromes P450 2C9- and 3A4-Mediated Drug Metabolism in Human Hepatocytes. Sci Pharm 78:473-81

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