Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR042005-03
Application #
2081196
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1993-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Svensjö, Erik; Saraiva, Elvira M; Amendola, Rafael Silveira et al. (2012) Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1-CXCR1/2-pathway. Microvasc Res 83:185-93
Lerner, Ethan A; Yosipovitch, Gil (2010) A tribute to Walter Shelley, a pioneer itch researcher (1917-2009). Arch Dermatol 146:788
Lerner, Ethan A; Iuga, Aurel O; Reddy, Vemuri B (2007) Maxadilan, a PAC1 receptor agonist from sand flies. Peptides 28:1651-4
Iuga, Aurel O; Qureshi, Abrar A; Lerner, Ethan A (2004) Nitric oxide is toxic to melanocytes in vitro. Pigment Cell Res 17:302-6
Pereira, Phyllis; Reddy, Vermuri B; Kounga, Kounga et al. (2002) Maxadilan activates PAC1 receptors expressed in Xenopus laevis xelanophores. Pigment Cell Res 15:461-6
Reddy, V B; Kounga, K; Mariano, F et al. (2000) Chrysoptin is a potent glycoprotein IIb/IIIa fibrinogen receptor antagonist present in salivary gland extracts of the deerfly. J Biol Chem 275:15861-7
Lerner, L H; Qureshi, A A; Reddy, B V et al. (2000) Nitric oxide synthase in toxic epidermal necrolysis and Stevens-Johnson syndrome. J Invest Dermatol 114:196-9
Moro, O; Wakita, K; Ohnuma, M et al. (1999) Functional characterization of structural alterations in the sequence of the vasodilatory peptide maxadilan yields a pituitary adenylate cyclase-activating peptide type 1 receptor-specific antagonist. J Biol Chem 274:23103-10
Moro, O; Lerner, E A (1997) Maxadilan, the vasodilator from sand flies, is a specific pituitary adenylate cyclase activating peptide type I receptor agonist. J Biol Chem 272:966-70
Qureshi, A A; Asahina, A; Ohnuma, M et al. (1996) Immunomodulatory properties of maxadilan, the vasodilator peptide from sand fly salivary gland extracts. Am J Trop Med Hyg 54:665-71

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