Insulin-Like Growth Factor II in Breast Cancer

Cullen, Kevin J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA058441-03
• Application #: 2099128
• Study Section: Reproductive Endocrinology Study Section (REN)
• Project Start: 1993-02-10
• Project End: 1997-01-31
• Budget Start: 1995-05-22
• Budget End: 1997-01-31
• Support Year: 3
• Fiscal Year: 1995

Institution

• Name: Georgetown University
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 049515844
• City: Washington
• State: DC
• Country: United States
• Zip Code: 20057

Publications

Singer, C F; Rasmussen, A; Lippman, M E et al. (1997) Coexpression of stromelysin-3 and insulin-like growth factor II in tumors of ectodermal, mesodermal, and endodermal origin: indicator of a fetal cell phenotype. J Clin Endocrinol Metab 82:1917-22

Ellis, M J; Leav, B A; Yang, Z et al. (1996) Affinity for the insulin-like growth factor-II (IGF-II) receptor inhibits autocrine IGF-II activity in MCF-7 breast cancer cells. Mol Endocrinol 10:286-97

Singer, C; Rasmussen, A; Smith, H S et al. (1995) Malignant breast epithelium selects for insulin-like growth factor II expression in breast stroma: evidence for paracrine function. Cancer Res 55:2448-54