Abstract

A case-control study of female breast cancer will be undertaken in the two largest hospitals serving residents of Long Island, a high-risk geographical area in New York State, in order to investigate new leads in breast cancer etiology. The primary aim is to study breast cancer risk in relation to levels of organochlorine compounds such as polychlorinated biphenyl (PCBs) and several once-common pesticides. Levels of these compounds will be measured in adipose tissue of breast cancer cases and two sets of matched controls, one consisting of women with benign breast disease and the other of women undergoing a variety of surgical procedures. A secondary aim is to study possible associations of breast cancer with (a) consumption of foods whose of preparation endows them with high levels of polycyclic aromatic hydrocarbons (PAH) and heterocyclic aromatic amines (HAA); (b) estrogen replacement therapy, especially in lean women; (c) occupational and other exposure to radiofrequency electromagnetic radiation; (d) other possible risk factors, such as heavy alcohol consumption.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA063021-01
Application #
2104586
Study Section
Special Emphasis Panel (SRC (94))
Project Start
1994-05-01
Project End
1997-02-28
Budget Start
1994-05-01
Budget End
1995-02-28
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
Institute for Cancer Prevention
Department
Type
DUNS #
City
Valhalla
State
NY
Country
United States
Zip Code
10595

  Publications

Beyea, Jan; Stellman, Steven D; Teitelbaum, Susan et al. (2013) Imputation method for lifetime exposure assessment in air pollution epidemiologic studies. Environ Health 12:62
Farooq, Umar; Joshi, Monika; Nookala, Vinod et al. (2010) Self-reported exposure to pesticides in residential settings and risk of breast cancer: a case-control study. Environ Health 9:30
Beyea, Jan; Stellman, Steven D; Hatch, Maureen et al. (2008) Airborne emissions from 1961 to 2004 of benzo[a]pyrene from U.S. vehicles per km of travel based on tunnel studies. Environ Sci Technol 42:7315-20
Beyea, Jan; Hatch, Maureen; Stellman, Steven D et al. (2006) Validation and calibration of a model used to reconstruct historical exposure to polycyclic aromatic hydrocarbons for use in epidemiologic studies. Environ Health Perspect 114:1053-8
Muscat, Joshua E; Britton, Julie A; Djordjevic, Mirjana V et al. (2003) Adipose concentrations of organochlorine compounds and breast cancer recurrence in Long Island, New York. Cancer Epidemiol Biomarkers Prev 12:1474-8
Stellman, S D; Djordjevic, M V; Britton, J A et al. (2000) Breast cancer risk in relation to adipose concentrations of organochlorine pesticides and polychlorinated biphenyls in Long Island, New York. Cancer Epidemiol Biomarkers Prev 9:1241-9
Stellman, S D; Djordjevic, M V; Muscat, J E et al. (1998) Relative abundance of organochlorine pesticides and polychlorinated biphenyls in adipose tissue and serum of women in Long Island, New York. Cancer Epidemiol Biomarkers Prev 7:489-96
Stellman, S D; Resnicow, K (1997) Tobacco smoking, cancer and social class. IARC Sci Publ :229-50
Garfinkel, L; Stellman, S D (1997) Breast cancer and Women & Health. Women Health 26:1-5
Stellman, S D (1996) Proportional mortality ratios among Korean immigrants to New York City, 1986-1990. Yonsei Med J 37:31-7

Showing the most recent 10 out of 12 publications