Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA013866-04
Application #
6634335
Study Section
Special Emphasis Panel (ZRG1-AARR-2 (01))
Program Officer
Pollock, Jonathan D
Project Start
2000-05-15
Project End
2005-02-28
Budget Start
2003-03-01
Budget End
2004-02-29
Support Year
4
Fiscal Year
2003
Total Cost
$241,033
Indirect Cost

  Institution

Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Pham, Hang M; Arganaraz, Enrique R; Groschel, Bettina et al. (2004) Lentiviral vectors interfering with virus-induced CD4 down-modulation potently block human immunodeficiency virus type 1 replication in primary lymphocytes. J Virol 78:13072-81
Arganaraz, Enrique R; Schindler, Michael; Kirchhoff, Frank et al. (2003) Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication. J Biol Chem 278:33912-9
Lama, Juan (2003) The physiological relevance of CD4 receptor down-modulation during HIV infection. Curr HIV Res 1:167-84
Cortes, Maria Jose; Wong-Staal, Flossie; Lama, Juan (2002) Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells. J Biol Chem 277:1770-9