Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC003573-02
Application #
6055843
Study Section
Hearing Research Study Section (HAR)
Project Start
1998-09-30
Project End
2003-08-31
Budget Start
1999-09-01
Budget End
2000-08-31
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Trune, Dennis R; Kempton, J Beth; Gross, Neil D (2006) Mineralocorticoid receptor mediates glucocorticoid treatment effects in the autoimmune mouse ear. Hear Res 212:22-32
Hefeneider, Steven H; McCoy, Sharon L; Hausman, Frances A et al. (2004) Autoimmune mouse antibodies recognize multiple antigens proposed in human immune-mediated hearing loss. Otol Neurotol 25:250-6
McCoy, Sharon L; Kurtz, Stephen E; Hausman, Frances A et al. (2004) Activation of RAW264.7 macrophages by bacterial DNA and lipopolysaccharide increases cell surface DNA binding and internalization. J Biol Chem 279:17217-23
Vass, Z; Dai, C F; Steyger, P S et al. (2004) Co-localization of the vanilloid capsaicin receptor and substance P in sensory nerve fibers innervating cochlear and vertebro-basilar arteries. Neuroscience 124:919-27
Pillers, De-Ann M; Kempton, J Beth; Duncan, Nancy M et al. (2002) Hearing loss in the laminin-deficient dy mouse model of congenital muscular dystrophy. Mol Genet Metab 76:217-24
Trune, Dennis R; Kempton, J Beth (2002) Female MRL.MpJ-Fas(lpr) autoimmune mice have greater hearing loss than males. Hear Res 167:170-4
Gross, Neil D; Kempton, J Beth; Trune, Dennis R (2002) Spironolactone blocks glucocorticoid-mediated hearing preservation in autoimmune mice. Laryngoscope 112:298-303
Vass, Z; Steyger, P S; Hordichok, A J et al. (2001) Capsaicin stimulation of the cochlea and electric stimulation of the trigeminal ganglion mediate vascular permeability in cochlear and vertebro-basilar arteries: a potential cause of inner ear dysfunction in headache. Neuroscience 103:189-201
Trune, D R; Kempton, J B (2001) Aldosterone and prednisolone control of cochlear function in MRL/MpJ-Fas(lpr) autoimmune mice. Hear Res 155:9-20
Kaylie, D M; Hefeneider, S H; Kempton, J B et al. (2001) Decreased cochlear DNA receptor staining in MRL.MpJ-Fas(lpr) autoimmune mice with hearing loss. Laryngoscope 111:1275-80

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