Glucocorticoid Receptor Function in Hypothalamic Cells

Defranco, Donald Benedict

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK047938-02
• Application #: 2147891
• Study Section: Biochemical Endocrinology Study Section (BCE)
• Project Start: 1995-03-01
• Project End: 1999-02-28
• Budget Start: 1996-05-04
• Budget End: 1997-02-28
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: University of Pittsburgh
• Department: Biology
• Type: Schools of Arts and Sciences
• DUNS #: 053785812
• City: Pittsburgh
• State: PA
• Country: United States
• Zip Code: 15213

Publications

Gore, Andrea C; Attardi, Barbara; DeFranco, Donald B (2006) Glucocorticoid repression of the reproductive axis: effects on GnRH and gonadotropin subunit mRNA levels. Mol Cell Endocrinol 256:40-8

Birder, L A; Barrick, S R; Roppolo, J R et al. (2003) Feline interstitial cystitis results in mechanical hypersensitivity and altered ATP release from bladder urothelium. Am J Physiol Renal Physiol 285:F423-9

Chandran, U R; Warren, B S; Baumann, C T et al. (1999) The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropin-releasing hormone distal negative glucocorticoid response element. J Biol Chem 274:2372-8

Attardi, B; Tsujii, T; Friedman, R et al. (1997) Glucocorticoid repression of gonadotropin-releasing hormone gene expression and secretion in morphologically distinct subpopulations of GT1-7 cells. Mol Cell Endocrinol 131:241-55

Chandran, U R; Attardi, B; Friedman, R et al. (1996) Glucocorticoid repression of the mouse gonadotropin-releasing hormone gene is mediated by promoter elements that are recognized by heteromeric complexes containing glucocorticoid receptor. J Biol Chem 271:20412-20