Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Research Project (R01)
Project #
5R01EB000226-03
Application #
6682854
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Program Officer
Korte, Brenda
Project Start
2001-07-01
Project End
2005-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
3
Fiscal Year
2003
Total Cost
$229,163
Indirect Cost
Name
University of Kansas Lawrence
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
076248616
City
Lawrence
State
KS
Country
United States
Zip Code
66045
Kiptoo, Paul; Sinaga, Ernawati; Calcagno, Anna M et al. (2011) Enhancement of drug absorption through the blood-brain barrier and inhibition of intercellular tight junction resealing by E-cadherin peptides. Mol Pharm 8:239-49
Zheng, Kai; Laurence, Jennifer S; Kuczera, Krzysztof et al. (2009) Characterization of multiple stable conformers of the EC5 domain of E-cadherin and the interaction of EC5 with E-cadherin peptides. Chem Biol Drug Des 73:584-98
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Zheng, Kai; Trivedi, Maulik; Siahaan, Teruna J (2006) Structure and function of the intercellular junctions: barrier of paracellular drug delivery. Curr Pharm Des 12:2813-24
Calcagno, Anna Maria; Fostel, Jennifer M; Orchekowski, Randal P et al. (2005) Modulation of cell adhesion molecules in various epithelial cell lines after treatment with PP2. Mol Pharm 2:170-84
Huang, Meng; Matthews, Kametra; Siahaan, Teruna J et al. (2005) Alpha L-integrin I domain cyclic peptide antagonist selectively inhibits T cell adhesion to pancreatic islet microvascular endothelium. Am J Physiol Gastrointest Liver Physiol 288:G67-73
Calcagno, Anna Maria; Fostel, Jennifer M; Reyner, Eric L et al. (2004) Effects of an E-cadherin-derived peptide on the gene expression of Caco-2 cells. Pharm Res 21:2085-94

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