Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES007589-05
Application #
2157029
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1995-03-01
Project End
1998-02-28
Budget Start
1996-02-29
Budget End
1997-02-28
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Other Clinical Sciences
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Kovalevskaya, G; Kakuma, T; Schlatterer, J et al. (2007) Hyperglycosylated HCG expression in pregnancy: cellular origin and clinical applications. Mol Cell Endocrinol 260-262:237-43
Kovalevskaya, G; Birken, S; Kakuma, T et al. (2002) Differential expression of human chorionic gonadotropin (hCG) glycosylation isoforms in failing and continuing pregnancies: preliminary characterization of the hyperglycosylated hCG epitope. J Endocrinol 172:497-506
Kovalevskaya, G; Genbacev, O; Fisher, S J et al. (2002) Trophoblast origin of hCG isoforms: cytotrophoblasts are the primary source of choriocarcinoma-like hCG. Mol Cell Endocrinol 194:147-55
Birken, S; Kovalevskaya, G; O'Connor, J (2001) Immunochemical measurement of early pregnancy isoforms of HCG: potential applications to fertility research, prenatal diagnosis, and cancer. Arch Med Res 32:635-43
Mock, P; Kovalevskaya, G; O'Connor, J F et al. (2000) Choriocarcinoma-like human chorionic gonadotrophin (HCG) and HCG bioactivity during the first trimester of pregnancy. Hum Reprod 15:2209-14
Birken, S; Krichevsky, A; O'Connor, J et al. (1999) Development and characterization of antibodies to a nicked and hyperglycosylated form of hCG from a choriocarcinoma patient: generation of antibodies that differentiate between pregnancy hCG and choriocarcinoma hCG. Endocrine 10:137-44
Kovalevskaya, G; Birken, S; Kakuma, T et al. (1999) Early pregnancy human chorionic gonadotropin (hCG) isoforms measured by an immunometric assay for choriocarcinoma-like hCG. J Endocrinol 161:99-106
Kovalevskaya, G; Birken, S; Kakuma, T et al. (1999) Evaluation of nicked human chorionic gonadotropin content in clinical specimens by a specific immunometric assay. Clin Chem 45:68-77
Birken, S; Santoro, N; Maydelman, Y et al. (1999) Differences in urinary excretion patterns of the hLH beta core fragment in premenopausal, perimenopausal, and postmenopausal women. Menopause 6:290-8
O'Connor, J F; Ellish, N; Kakuma, T et al. (1998) Differential urinary gonadotrophin profiles in early pregnancy and early pregnancy loss. Prenat Diagn 18:1232-40

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