Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM031489-12
Application #
2176151
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1983-02-01
Project End
1997-01-31
Budget Start
1994-02-01
Budget End
1997-01-31
Support Year
12
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Guha, A; Dashner, K; Black, P M et al. (1995) Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int J Cancer 60:168-73
Segal, R A; Pomeroy, S L; Stiles, C D (1995) Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells. J Neurosci 15:4970-81
Wang, C; Stiles, C D (1994) Platelet-derived growth factor alpha receptor gene expression: isolation and characterization of the promoter and upstream regulatory elements. Proc Natl Acad Sci U S A 91:7061-5
Segal, R A; Goumnerova, L C; Kwon, Y K et al. (1994) Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci U S A 91:12867-71
Shamah, S M; Stiles, C D; Guha, A (1993) Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells. Mol Cell Biol 13:7203-12
Wang, C; Shamah, S M; Stiles, C D (1992) Recombinant PDGF from lower vertebrates: receptor binding and immunochemical analysis with metabolically labeled growth factor. Growth Factors 7:279-88
Oquendo, P; Alberta, J; Wen, D Z et al. (1989) The platelet-derived growth factor-inducible KC gene encodes a secretory protein related to platelet alpha-granule proteins. J Biol Chem 264:4133-7
Hall, D J; Stiles, C D (1987) Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers. J Biol Chem 262:15302-8
Rollins, B J; Morrison, E D; Stiles, C D (1987) A cell-cycle constraint on the regulation of gene expression by platelet-derived growth factor. Science 238:1269-71
Zumstein, P; Stiles, C D (1987) Molecular cloning of gene sequences that are regulated by insulin-like growth factor I. J Biol Chem 262:11252-60

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