Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
9R01GM053824-13
Application #
2193237
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1984-07-01
Project End
1999-11-30
Budget Start
1995-12-08
Budget End
1996-11-30
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Stellwagen, A E; Craig, N L (2001) Analysis of gain-of-function mutants of an ATP-dependent regulator of Tn7 transposition. J Mol Biol 305:633-42
Peters, J E; Craig, N L (2001) Tn7 recognizes transposition target structures associated with DNA replication using the DNA-binding protein TnsE. Genes Dev 15:737-47
Rao, J E; Craig, N L (2001) Selective recognition of pyrimidine motif triplexes by a protein encoded by the bacterial transposon Tn7. J Mol Biol 307:1161-70
Kuduvalli, P N; Rao, J E; Craig, N L (2001) Target DNA structure plays a critical role in Tn7 transposition. EMBO J 20:924-32
Rao, J E; Miller, P S; Craig, N L (2000) Recognition of triple-helical DNA structures by transposon Tn7. Proc Natl Acad Sci U S A 97:3936-41
Biery, M C; Stewart, F J; Stellwagen, A E et al. (2000) A simple in vitro Tn7-based transposition system with low target site selectivity for genome and gene analysis. Nucleic Acids Res 28:1067-77
Peters, J E; Craig, N L (2000) Tn7 transposes proximal to DNA double-strand breaks and into regions where chromosomal DNA replication terminates. Mol Cell 6:573-82
Sharpe, P L; Craig, N L (1998) Host proteins can stimulate Tn7 transposition: a novel role for the ribosomal protein L29 and the acyl carrier protein. EMBO J 17:5822-31
Gwinn, M L; Stellwagen, A E; Craig, N L et al. (1997) In vitro Tn7 mutagenesis of Haemophilus influenzae Rd and characterization of the role of atpA in transformation. J Bacteriol 179:7315-20
Stellwagen, A E; Craig, N L (1997) Avoiding self: two Tn7-encoded proteins mediate target immunity in Tn7 transposition. EMBO J 16:6823-34

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