Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM067935-02
Application #
6696292
Study Section
Special Emphasis Panel (ZGM1-MBP-1 (ME))
Program Officer
Jones, Warren
Project Start
2003-01-08
Project End
2005-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$274,600
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Hancock, Kathy; Narang, Someet; Pattabhi, Sowmya et al. (2008) False positive reactivity of recombinant, diagnostic, glycoproteins produced in High Five insect cells: effect of glycosylation. J Immunol Methods 330:130-6
Kim, Yeon Kyu; Shin, Hwa Sung; Tomiya, Noboru et al. (2005) Production and N-glycan analysis of secreted human erythropoietin glycoprotein in stably transfected Drosophila S2 cells. Biotechnol Bioeng 92:452-61
Viswanathan, Karthik; Narang, Someet; Hinderlich, Stephan et al. (2005) Engineering intracellular CMP-sialic acid metabolism into insect cells and methods to enhance its generation. Biochemistry 44:7526-34
Betenbaugh, Michael J; Tomiya, Noboru; Narang, Someet et al. (2004) Biosynthesis of human-type N-glycans in heterologous systems. Curr Opin Struct Biol 14:601-6
Tomiya, Noboru; Narang, Someet; Lee, Yuan C et al. (2004) Comparing N-glycan processing in mammalian cell lines to native and engineered lepidopteran insect cell lines. Glycoconj J 21:343-60
Viswanathan, Karthik; Lawrence, Shawn; Hinderlich, Stephan et al. (2003) Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them. Biochemistry 42:15215-25