The goal of the Gene Ontology (GO) consortium is to provide shared, structured vocabularies for the biological description of gene products in any organism. This work includes building three extensive ontologies; those for molecular function, biological process and cellular components. These terms will be used to annotate gene products in databases of the consortium members. Further, a repository database and public Web pages will be created to allow querying for these terms across annotated datasets provided by the model organism databases. The GO consortium, initiated in 1998, is currently a collaboration among three model organism databases: FlyBase, the Saccharomyces Genome Database (SGD), and the Mouse Genome Informatics databases (MGD/GXD). It is our intention for this consortium to be joined by others who are annotating attributes of gene products for other species.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Research Project (R01)
Project #
5R01HG002273-02
Application #
6490272
Study Section
Genome Study Section (GNM)
Program Officer
Peterson, Jane
Project Start
2001-01-19
Project End
2003-12-31
Budget Start
2002-01-01
Budget End
2002-12-31
Support Year
2
Fiscal Year
2002
Total Cost
$1,796,613
Indirect Cost
Name
Jackson Laboratory
Department
Type
DUNS #
042140483
City
Bar Harbor
State
ME
Country
United States
Zip Code
04609
Christie, Karen R; Blake, Judith A (2018) Sensing the cilium, digital capture of ciliary data for comparative genomics investigations. Cilia 7:3
Huntley, Rachael P; Sitnikov, Dmitry; Orlic-Milacic, Marija et al. (2016) Guidelines for the functional annotation of microRNAs using the Gene Ontology. RNA 22:667-76
Shaw, David R (2016) Searching the Mouse Genome Informatics (MGI) Resources for Information on Mouse Biology from Genotype to Phenotype. Curr Protoc Bioinformatics 56:1.7.1-1.7.16
Diehl, Alexander D; Meehan, Terrence F; Bradford, Yvonne M et al. (2016) The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability. J Biomed Semantics 7:44
Alam-Faruque, Yasmin; Hill, David P; Dimmer, Emily C et al. (2014) Representing kidney development using the gene ontology. PLoS One 9:e99864
Mutowo-Meullenet, Prudence; Huntley, Rachael P; Dimmer, Emily C et al. (2013) Use of Gene Ontology Annotation to understand the peroxisome proteome in humans. Database (Oxford) 2013:bas062
Ta?an, Murat; Drabkin, Harold J; Beaver, John E et al. (2012) A Resource of Quantitative Functional Annotation for Homo sapiens Genes. G3 (Bethesda) 2:223-33
Drabkin, Harold J; Blake, Judith A; Mouse Genome Informatics Database (2012) Manual Gene Ontology annotation workflow at the Mouse Genome Informatics Database. Database (Oxford) 2012:bas045
Diehl, Alexander D; Augustine, Alison Deckhut; Blake, Judith A et al. (2011) Hematopoietic cell types: prototype for a revised cell ontology. J Biomed Inform 44:75-9
Alam-Faruque, Yasmin; Huntley, Rachael P; Khodiyar, Varsha K et al. (2011) The impact of focused Gene Ontology curation of specific mammalian systems. PLoS One 6:e27541

Showing the most recent 10 out of 27 publications