Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL027317-06
Application #
3339078
Study Section
(SSS)
Project Start
1988-07-01
Project End
1988-12-31
Budget Start
1988-07-01
Budget End
1988-12-31
Support Year
6
Fiscal Year
1986
Total Cost
Indirect Cost
Name
San Francisco State University
Department
Type
Schools of Arts and Sciences
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94132
Sastry, S S; Kun, E (1990) The interaction of adenosine diphosphoribosyl transferase (ADPRT) with a cruciform DNA. Biochem Biophys Res Commun 167:842-7
Sastry, S S; Buki, K G; Kun, E (1989) Binding of adenosine diphosphoribosyltransferase to the termini and internal regions of linear DNAs. Biochemistry 28:5670-80
Sooki-Toth, A; Banfalvi, G; Szollosi, J et al. (1989) Cellular regulation of ADP-ribosylation of proteins. III. Selective augmentation of in vitro ADP-ribosylation of histone H3 in murine thymic cells after in vivo emetine treatment. Exp Cell Res 184:44-52
Buki, K G; Kun, E (1988) Polypeptide domains of ADP-ribosyltransferase obtained by digestion with plasmin. Biochemistry 27:5990-5
Kun, E (1988) Probable macromolecular mechanisms of gene regulation by adenosine diphosphoribosyl transferase (ADPRT). Adv Exp Med Biol 231:613-26
Sastry, S S; Kun, E (1988) Molecular interactions between DNA, poly(ADP-ribose) polymerase, and histones. J Biol Chem 263:1505-12
Sooki-Toth, A; Asghari, F; Kirsten, E et al. (1987) Cellular regulation of poly ADP-ribosylation of proteins. II. Augmentation of poly(ADP-ribose) polymerase in SV40 3T3 cells following methotrexate-induced G1/S inhibition of cell cycle progression. Exp Cell Res 170:93-102
Tseng Jr, A; Lee, W M; Jakobovits, E B et al. (1987) Prevention of tumorigenesis of oncogene-transformed rat fibroblasts with DNA site inhibitors of poly(ADP ribose) polymerase. Proc Natl Acad Sci U S A 84:1107-11
McLick, J; Hakam, A; Bauer, P I et al. (1987) Benzamide-DNA interactions: deductions from binding, enzyme kinetics and from X-ray structural analysis of a 9-ethyladenine-benzamide adduct. Biochim Biophys Acta 909:71-83
Hakam, A; McLick, J; Buki, K et al. (1987) Catalytic activities of synthetic octadeoxyribonucleotides as coenzymes of poly(ADP-ribose) polymerase and the identification of a new enzyme inhibitory site. FEBS Lett 212:73-8

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