Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL046022-03
Application #
3365163
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1992-05-01
Project End
1995-04-30
Budget Start
1993-12-15
Budget End
1994-04-30
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Sidney Kimmel Cancer Center
Department
Type
DUNS #
City
San Diego
State
CA
Country
United States
Zip Code
92121
Lehr, H A; Weyrich, A S; Saetzler, R K et al. (1997) Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest 99:2358-64
Thiel, M; Zourelidis, C; Chambers, J D et al. (1997) Expression of beta 2-integrins and L-selectin on polymorphonuclear leukocytes in septic patients. Eur Surg Res 29:160-75
Saetzler, R K; Jallo, J; Lehr, H A et al. (1997) Intravital fluorescence microscopy: impact of light-induced phototoxicity on adhesion of fluorescently labeled leukocytes. J Histochem Cytochem 45:505-13
Thiel, M; Chambers, J D; Chouker, A et al. (1996) Effect of adenosine on the expression of beta(2) integrins and L-selectin of human polymorphonuclear leukocytes in vitro. J Leukoc Biol 59:671-82
Lehr, H A; Frei, B; Olofsson, A M et al. (1995) Protection from oxidized LDL-induced leukocyte adhesion to microvascular and macrovascular endothelium in vivo by vitamin C but not by vitamin E. Circulation 91:1525-32
Vajkoczy, P; Olofsson, A M; Lehr, H A et al. (1995) Histogenesis and ultrastructure of pancreatic islet graft microvasculature. Evidence for graft revascularization by endothelial cells of host origin. Am J Pathol 146:1397-405
Jagels, M A; Chambers, J D; Arfors, K E et al. (1995) C5a- and tumor necrosis factor-alpha-induced leukocytosis occurs independently of beta 2 integrins and L-selectin: differential effects on neutrophil adhesion molecule expression in vivo. Blood 85:2900-9
Mazzoni, M C; Warnke, K C; Arfors, K E et al. (1994) Capillary hemodynamics in hemorrhagic shock and reperfusion: in vivo and model analysis. Am J Physiol 267:H1928-35
Olofsson, A M; Arfors, K E; Ramezani, L et al. (1994) E-selectin mediates leukocyte rolling in interleukin-1-treated rabbit mesentery venules. Blood 84:2749-58
Lehr, H A; Olofsson, A M; Carew, T E et al. (1994) P-selectin mediates the interaction of circulating leukocytes with platelets and microvascular endothelium in response to oxidized lipoprotein in vivo. Lab Invest 71:380-6

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