Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL052040-03
Application #
2229166
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1994-04-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Narita, M; Rudolph, A E; Miletich, J P et al. (1998) The low-density lipoprotein receptor-related protein (LRP) mediates clearance of coagulation factor Xa in vivo. Blood 91:555-60
Warshawsky, I; Herz, J; Broze Jr, G J et al. (1996) The low density lipoprotein receptor-related protein can function independently from heparan sulfate proteoglycans in tissue factor pathway inhibitor endocytosis. J Biol Chem 271:25873-9
Warshawsky, I; Schwartz, A L (1996) The 39-kDa protein regulates LRP activity in cultured endothelial and smooth muscle cells. Eur J Cell Biol 69:156-65
Warshawsky, I; Bu, G; Mast, A et al. (1995) The carboxy terminus of tissue factor pathway inhibitor is required for interacting with hepatoma cells in vitro and in vivo. J Clin Invest 95:1773-81
Narita, M; Bu, G; Olins, G M et al. (1995) Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo. J Biol Chem 270:24800-4
Bu, G; Geuze, H J; Strous, G J et al. (1995) 39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related protein. EMBO J 14:2269-80
Nielsen, M S; Nykjaer, A; Warshawsky, I et al. (1995) Analysis of ligand binding to the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that lipoprotein lipase and the carboxyl-terminal domain of the receptor-associated protein bind to the same site. J Biol Chem 270:23713-9
Warshawsky, I; Bu, G; Schwartz, A L (1995) Sites within the 39-kDa protein important for regulating ligand binding to the low-density lipoprotein receptor-related protein. Biochemistry 34:3404-15
Narita, M; Bu, G; Herz, J et al. (1995) Two receptor systems are involved in the plasma clearance of tissue-type plasminogen activator (t-PA) in vivo. J Clin Invest 96:1164-8
Bu, G; Maksymovitch, E A; Nerbonne, J M et al. (1994) Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons. J Biol Chem 269:18521-8

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