Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL054810-02
Application #
2233275
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1995-07-01
Project End
2000-05-31
Budget Start
1996-06-15
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Eastern Virginia Medical School
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Norfolk
State
VA
Country
United States
Zip Code
23501
Dobrian, Anca D; Schriver, Suzanne D; Lynch, Terrie et al. (2003) Effect of salt on hypertension and oxidative stress in a rat model of diet-induced obesity. Am J Physiol Renal Physiol 285:F619-28
Dobrian, A D; Davies, M J; Schriver, S D et al. (2001) Oxidative stress in a rat model of obesity-induced hypertension. Hypertension 37:554-60
Wesselman, J P; Dobrian, A D; Schriver, S D et al. (2001) Src tyrosine kinases and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinases mediate pressure-induced c-fos expression in cannulated rat mesenteric small arteries. Hypertension 37:955-60
Parker, S B; Dobrian, A D; Wade, S S et al. (2000) AT(1) receptor inhibition does not reduce arterial wall hypertrophy or PDGF-A expression in renal hypertension. Am J Physiol Heart Circ Physiol 278:H613-22
Dobrian, A D; Davies, M J; Prewitt, R L et al. (2000) Development of hypertension in a rat model of diet-induced obesity. Hypertension 35:1009-15
Dobrian, A; Wade, S S; Prewitt, R L (1999) PDGF-A expression correlates with blood pressure and remodeling in 1K1C hypertensive rat arteries. Am J Physiol 276:H2159-67
Miriel, V A; Allen, S P; Schriver, S D et al. (1999) Genistein inhibits pressure-induced expression of c-fos in isolated mesenteric arteries. Hypertension 34:132-7
Tulis, D A; Prewitt, R L (1998) Medial and endothelial platelet-derived growth factor A chain expression is regulated by in vivo exposure to elevated flow. J Vasc Res 35:413-20
Parker, S B; Wade, S S; Prewitt, R L (1998) Pressure mediates angiotensin II-induced arterial hypertrophy and PDGF-A expression. Hypertension 32:452-8
Allen, S P; Wade, S S; Prewitt, R L (1997) Myogenic tone attenuates pressure-induced gene expression in isolated small arteries. Hypertension 30:203-8