Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL067244-02
Application #
6690736
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Program Officer
Goldman, Stephen
Project Start
2002-12-16
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$187,500
Indirect Cost
Name
Medical College of Wisconsin
Department
Biophysics
Type
Schools of Medicine
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Whitsett, Jennifer; Rangel Filho, Artur; Sethumadhavan, Savitha et al. (2013) Human endothelial dihydrofolate reductase low activity limits vascular tetrahydrobiopterin recycling. Free Radic Biol Med 63:143-50
Sethumadhavan, Savitha; Vasquez-Vivar, Jeannette; Migrino, Raymond Q et al. (2012) Mitochondrial DNA variant for complex I reveals a role in diabetic cardiac remodeling. J Biol Chem 287:22174-82
Leskov, Igor L; Whitsett, Jennifer; Vasquez-Vivar, Jeannette et al. (2011) NAD(P)H oxidase and eNOS play differential roles in cytomegalovirus infection-induced microvascular dysfunction. Free Radic Biol Med 51:2300-8
Belik, Jaques; McIntyre, Brendan A S; Enomoto, Masahiro et al. (2011) Pulmonary hypertension in the newborn GTP cyclohydrolase I-deficient mouse. Free Radic Biol Med 51:2227-33
Ji, Haitao; Tan, Sidhartha; Igarashi, Jotaro et al. (2009) Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy. Ann Neurol 65:209-17
Pieper, Galen M; Ionova, Irina A; Cooley, Brian C et al. (2009) Sepiapterin decreases acute rejection and apoptosis in cardiac transplants independently of changes in nitric oxide and inducible nitric-oxide synthase dimerization. J Pharmacol Exp Ther 329:890-9
Du, Jianhai; Wei, Na; Xu, Hao et al. (2009) Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I. Arterioscler Thromb Vasc Biol 29:2161-8
Hein, Travis W; Singh, Uma; Vasquez-Vivar, Jeannette et al. (2009) Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo. Atherosclerosis 206:61-8
Vásquez-Vivar, Jeannette (2009) Tetrahydrobiopterin, superoxide, and vascular dysfunction. Free Radic Biol Med 47:1108-19
Zielonka, Jacek; Srinivasan, Satish; Hardy, Micael et al. (2008) Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: identification of homo- and heterodimers. Free Radic Biol Med 44:835-46

Showing the most recent 10 out of 27 publications