Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL071806-02
Application #
6693301
Study Section
Cardiovascular and Renal Study Section (CVB)
Program Officer
Lin, Michael
Project Start
2003-01-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$286,000
Indirect Cost
Name
Henry Ford Health System
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073134603
City
Detroit
State
MI
Country
United States
Zip Code
48202
Worou, Morel E; Liao, Tang-Dong; D'Ambrosio, Martin et al. (2015) Renal protective effect of N-acetyl-seryl-aspartyl-lysyl-proline in dahl salt-sensitive rats. Hypertension 66:816-22
González, Germán E; Rhaleb, Nour-Eddine; Nakagawa, Pablo et al. (2014) N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats. Clin Sci (Lond) 126:85-94
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Peng, Hongmei; Carretero, Oscar A; Peterson, Edward L et al. (2012) N-Acetyl-seryl-aspartyl-lysyl-proline inhibits ET-1-induced collagen production by preserving Src homology 2-containing protein tyrosine phosphatase-2 activity in cardiac fibroblasts. Pflugers Arch 464:415-23
Zhu, Liping; Carretero, Oscar A; Xu, Jiang et al. (2012) Angiotensin II type 2 receptor-stimulated activation of plasma prekallikrein and bradykinin release: role of SHP-1. Am J Physiol Heart Circ Physiol 302:H2553-9
Rhaleb, Nour-Eddine; Pokharel, Saraswati; Sharma, Umesh et al. (2011) Renal protective effects of N-acetyl-Ser-Asp-Lys-Pro in deoxycorticosterone acetate-salt hypertensive mice. J Hypertens 29:330-8
Rhaleb, Nour-Eddine; Yang, Xiao-Ping; Carretero, Oscar A (2011) The kallikrein-kinin system as a regulator of cardiovascular and renal function. Compr Physiol 1:971-93
Peng, Hongmei; Yang, Xiao-Ping; Carretero, Oscar A et al. (2011) Angiotensin II-induced dilated cardiomyopathy in Balb/c but not C57BL/6J mice. Exp Physiol 96:756-64

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