We are requesting two years of funding to complete a clinical trial investigating the potential mechanisms of change in Cognitive Therapy for depression. Although all data collection procedures for the acute treatment phase of the study will be complete by the end of the current funding period, we need funds to complete a two-year follow-up, reduce and analyze follow-up data, and disseminate the findings. We have assigned depressed outpatients (N+152) to receive: (1) interventions aimed at activity scheduling and increasing pleasant events (the AC or """"""""behavioral activation"""""""" treatment, , testing an activation hypothesis for the efficacy of CT); (2) interventions aimed at behavioral targets and the examination/modification of dysfunctional automatic thoughts (the AT treatment, testing a """"""""coping skills"""""""" hypothesis for treatment efficacy); or (3) interventions aimed at behavioral activation, automatic thoughts and the structural modification of depressive schemas. This latter treatment represents standard CT. If Beck's hypothesis about the efficacy of CT is correct, the CT condition which includes schema modification should prove to be more durable in its ability to prevent depressive relapse, and might also be expected to outperform BA and AT during the acute treatment phase.
A second aim of the study has been to ascertain the degree to which all three treatments result in 1) behavioral activation; 2) increased ability to cope with depressogenic automatic thoughts; and 3) the extent to which core schema regarding the self are modified during the course of therapy. The assessment of these client changes provides a second, correlational examination of the processes leading to change during CT.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
2R01MH044063-06
Application #
2245972
Study Section
Treatment Assessment Review Committee (TA)
Project Start
1989-04-01
Project End
1996-03-31
Budget Start
1994-05-01
Budget End
1995-03-31
Support Year
6
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Washington
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Jacobson, N S; Gortner, E T (2000) Can depression be de-medicalized in the 21st century: scientific revolutions, counter-revolutions and the magnetic field of normal science. Behav Res Ther 38:103-17
Gortner, E T; Gollan, J K; Dobson, K S et al. (1998) Cognitive-behavioral treatment for depression: relapse prevention. J Consult Clin Psychol 66:377-84
Addis, M E; Jacobson, N S (1996) Reasons for depression and the process and outcome of cognitive-behavioral psychotherapies. J Consult Clin Psychol 64:1417-24
Jacobson, N S; Dobson, K S; Truax, P A et al. (1996) A component analysis of cognitive-behavioral treatment for depression. J Consult Clin Psychol 64:295-304
Waltz, J; Addis, M E; Koerner, K et al. (1993) Testing the integrity of a psychotherapy protocol: assessment of adherence and competence. J Consult Clin Psychol 61:620-30
Jacobson, N S; Truax, P (1991) Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. J Consult Clin Psychol 59:12-9