Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS023017-10
Application #
2264683
Study Section
Toxicology Subcommittee 2 (TOX)
Program Officer
Oliver, Eugene J
Project Start
1985-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1997-11-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Neurology
Type
Schools of Medicine
DUNS #
114400633
City
New York
State
NY
Country
United States
Zip Code
10029
Figueiredo-Pereira, M E; Cohen, G (1999) The ubiquitin/proteasome pathway: friend or foe in zinc-, cadmium-, and H2O2-induced neuronal oxidative stress. Mol Biol Rep 26:65-9
Mytilineou, C; Leonardi, E K; Radcliffe, P et al. (1998) Deprenyl and desmethylselegiline protect mesencephalic neurons from toxicity induced by glutathione depletion. J Pharmacol Exp Ther 284:700-6
Figueiredo-Pereira, M E; Yakushin, S; Cohen, G (1998) Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cells. J Biol Chem 273:12703-9
Dembiec-Cohen, D (1998) Mazindol, nomifensine and desmethylimipramine inhibit potassium-induced release of dopamine: effect of stimulus strength. J Neural Transm 105:735-47
Cohen, G; Yakushin, S; Dembiec-Cohen, D (1998) Protein L-dopa as an index of hydroxyl radical attack on protein tyrosine. Anal Biochem 263:232-9
Ogwu, V; Cohen, G (1998) A simple colorimetric method for the simultaneous determination of N-acetylcysteine and cysteine. Free Radic Biol Med 25:362-4
Hou, J G; Cohen, G; Mytilineou, C (1997) Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: involvement of the glutathione system. J Neurochem 69:76-83
Cohen, G; Farooqui, R; Kesler, N (1997) Parkinson disease: a new link between monoamine oxidase and mitochondrial electron flow. Proc Natl Acad Sci U S A 94:4890-4
Figueiredo-Pereira, M E; Yakushin, S; Cohen, G (1997) Accumulation of ubiquitinated proteins in mouse neuronal cells induced by oxidative stress. Mol Biol Rep 24:35-8
Han, S K; Cohen, G (1996) Inhibition of catalase in mesencephalic cultures by L-DOPA and dopamine. Neurochem Int 29:645-9

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