Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS035148-01
Application #
2274476
Study Section
Neurology C Study Section (NEUC)
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Segal, Rosalind A (2003) Selectivity in neurotrophin signaling: theme and variations. Annu Rev Neurosci 26:299-330
Ginty, David D; Segal, Rosalind A (2002) Retrograde neurotrophin signaling: Trk-ing along the axon. Curr Opin Neurobiol 12:268-74
Heerssen, Heather M; Segal, Rosalind A (2002) Location, location, location: a spatial view of neurotrophin signal transduction. Trends Neurosci 25:160-5
Bhattacharyya, Anita; Watson, Fiona L; Pomeroy, Scott L et al. (2002) High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors. J Neurobiol 51:302-12
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Choi, D Y; Toledo-Aral, J J; Segal, R et al. (2001) Sustained signaling by phospholipase C-gamma mediates nerve growth factor-triggered gene expression. Mol Cell Biol 21:2695-705
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Watson, F L; Porcionatto, M A; Bhattacharyya, A et al. (1999) TrkA glycosylation regulates receptor localization and activity. J Neurobiol 39:323-36
Watson, F L; Heerssen, H M; Moheban, D B et al. (1999) Rapid nuclear responses to target-derived neurotrophins require retrograde transport of ligand-receptor complex. J Neurosci 19:7889-900
Schwartz, P M; Borghesani, P R; Levy, R L et al. (1997) Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning. Neuron 19:269-81

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