Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS041962-02
Application #
6688986
Study Section
Molecular, Cellular and Developmental Neurosciences 2 (MDCN)
Program Officer
Owens, David F
Project Start
2002-12-15
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$344,375
Indirect Cost
Name
University of Alabama Birmingham
Department
Pathology
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Kaza, Niroop; Kohli, Latika; Graham, Christopher D et al. (2014) BNIP3 regulates AT101 [(-)-gossypol] induced death in malignant peripheral nerve sheath tumor cells. PLoS One 9:e96733
Kohli, Latika; Kaza, Niroop; Coric, Tatjana et al. (2013) 4-Hydroxytamoxifen induces autophagic death through K-Ras degradation. Cancer Res 73:4395-405
Kohli, Latika; Kaza, Niroop; Carroll, Steven L et al. (2013) Protector turns predator: Autophagic death via selective degradation of KRAS. Autophagy 9:1438-9
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Ghosh, Arindam P; Klocke, Barbara J; Ballestas, Mary E et al. (2012) CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress. PLoS One 7:e39586
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Ghosh, Arindam P; Cape, Jennifer D; Klocke, Barbara J et al. (2011) Deficiency of pro-apoptotic Hrk attenuates programmed cell death in the developing murine nervous system but does not affect Bcl-x deficiency-induced neuron apoptosis. J Histochem Cytochem 59:976-83
Pivtoraiko, Violetta N; Harrington, Adam J; Mader, Burton J et al. (2010) Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction. J Neurochem 114:1193-204
Kohli, Latika; Roth, Kevin A (2010) Autophagy: cerebral home cooking. Am J Pathol 176:1065-71
Geng, Ying; Walls, K C; Ghosh, Arindam P et al. (2010) Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. J Histochem Cytochem 58:265-75

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