Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DE010153-05
Application #
2131112
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1992-09-30
Project End
1998-06-30
Budget Start
1996-09-30
Budget End
1998-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Iowa
Department
Dentistry
Type
Schools of Dentistry
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Johnson, G K; Payne, J B; Fili, J M et al. (1998) Development of smokeless tobacco-induced oral mucosal lesions. J Oral Pathol Med 27:388-94
Payne, J B; Johnson, G K; Reinhardt, R A et al. (1998) Histological alterations following short-term smokeless tobacco exposure in humans. J Periodontal Res 33:274-9
Ringdahl, B E; Johnson, G K; Ali, R B et al. (1997) Effect of nicotine on arachidonic acid metabolites and epithelial parameters in rat oral mucosa. J Oral Pathol Med 26:40-5
Johnson, G K; Organ, C C (1997) Prostaglandin E2 and interleukin-1 concentrations in nicotine-exposed oral keratinocyte cultures. J Periodontal Res 32:447-54
Payne, J B; Johnson, G K; Reinhardt, R A et al. (1996) Nicotine effects on PGE2 and IL-1 beta release by LPS-treated human monocytes. J Periodontal Res 31:99-104
Johnson, G K; Poore, T K; Payne, J B et al. (1996) Effect of smokeless tobacco extract on human gingival keratinocyte levels of prostaglandin E2 and interleukin-1. J Periodontol 67:116-24
Poore, T K; Johnson, G K; Reinhardt, R A et al. (1995) The effects of smokeless tobacco on clinical parameters of inflammation and gingival crevicular fluid prostaglandin E2, interleukin-1 alpha, and interleukin-1 beta. J Periodontol 66:177-83
Johnson, G K; Poore, T K; Squier, C A et al. (1994) Prostaglandin E2 and interleukin-1 levels in smokeless tobacco-induced oral mucosal lesions. J Periodontal Res 29:430-8
Chen, Y P; Johnson, G K; Squier, C A (1994) Effects of nicotine and tobacco-specific nitrosamines on hamster cheek pouch and gastric mucosa. J Oral Pathol Med 23:251-5
Johnson, G K; Squier, C A (1993) Smokeless tobacco use by youth: a health concern. Pediatr Dent 15:169-74