Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM051428-03
Application #
2189953
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1994-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Pediatrics
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Sommer, Debbie; Coleman, Stacy; Swanson, Stanley A et al. (2002) Differential susceptibilities of serine/threonine phosphatases to oxidative and nitrosative stress. Arch Biochem Biophys 404:271-8
Feng, B; Stemmer, P M (2001) Ca2+ binding site 2 in calcineurin-B modulates calmodulin-dependent calcineurin phosphatase activity. Biochemistry 40:8808-14
Sommer, D; Fakata, K L; Swanson, S A et al. (2000) Modulation of the phosphatase activity of calcineurin by oxidants and antioxidants in vitro. Eur J Biochem 267:2312-22
Feng, B; Stemmer, P M (1999) Interactions of calcineurin A, calcineurin B, and Ca2+. Biochemistry 38:12481-9
Fakata, K L; Elmquist, W F; Swanson, S A et al. (1998) Cyclosporin A has low potency as a calcineurin inhibitor in cells expressing high levels of P-glycoprotein. Life Sci 62:2441-8