Schaefer, Christin M; Lu, Rui; Nesbitt, Natasha M et al. (2015) FadA5 a thiolase from Mycobacterium tuberculosis: a steroid-binding pocket reveals the potential for drug development against tuberculosis. Structure 23:21-33
|
Gao, Jin; Sampson, Nicole S (2014) A GMC oxidoreductase homologue is required for acetylation of glycopeptidolipid in Mycobacterium smegmatis. Biochemistry 53:611-3
|
Wipperman, Matthew F; Sampson, Nicole S; Thomas, Suzanne T (2014) Pathogen roid rage: cholesterol utilization by Mycobacterium tuberculosis. Crit Rev Biochem Mol Biol 49:269-93
|
Yang, Meng; Guja, Kip E; Thomas, Suzanne T et al. (2014) A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis. ACS Chem Biol 9:2632-45
|
Thomas, Suzanne T; Yang, Xinxin; Sampson, Nicole S (2011) Inhibition of the M. tuberculosis 3?-hydroxysteroid dehydrogenase by azasteroids. Bioorg Med Chem Lett 21:2216-9
|
Yang, Xinxin; Gao, Jin; Smith, Issar et al. (2011) Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection. J Bacteriol 193:1473-6
|
Nesbitt, Natasha M; Yang, Xinxin; Fontán, Patricia et al. (2010) A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol. Infect Immun 78:275-82
|
Kreit, Joseph; Sampson, Nicole S (2009) Cholesterol oxidase: physiological functions. FEBS J 276:6844-56
|