Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
5R35CA049734-07
Application #
2093413
Study Section
Special Emphasis Panel (SRC (88))
Project Start
1989-09-08
Project End
1997-12-31
Budget Start
1995-09-01
Budget End
1997-12-31
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Stanford University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305
Michie, S A; Sytwu, H K; McDevitt, J O et al. (1998) The roles of alpha 4-integrins in the development of insulin-dependent diabetes mellitus. Curr Top Microbiol Immunol 231:65-83
Yang, X D; Sytwu, H K; McDevitt, H O et al. (1997) Involvement of beta 7 integrin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the development of diabetes in obese diabetic mice. Diabetes 46:1542-7
Sytwu, H K; Liblau, R S; McDevitt, H O (1996) The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity 5:17-30
Fugger, L; Rothbard, J B; Sonderstrup-McDevitt, G (1996) Specificity of an HLA-DRB1*0401-restricted T cell response to type II collagen. Eur J Immunol 26:928-33
McDermott, M; Kastner, D L; Holloman, J D et al. (1995) The role of T cell receptor beta chain genes in susceptibility to rheumatoid arthritis. Arthritis Rheum 38:91-5
McDermott, M; Hsu, C; Molloy, M G et al. (1995) Non-linkage of a T-cell receptor gamma chain microsatellite (D7S485) to rheumatoid arthritis in multiplex families. J Autoimmun 8:131-8
Gelber, C; Paborsky, L; Singer, S et al. (1994) Isolation of nonobese diabetic mouse T-cells that recognize novel autoantigens involved in the early events of diabetes. Diabetes 43:33-9
Yang, X D; Michie, S A; Tisch, R et al. (1994) A predominant role of integrin alpha 4 in the spontaneous development of autoimmune diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A 91:12604-8
Yang, X D; McDevitt, H O (1994) Role of TNF-alpha in the development of autoimmunity and the pathogenesis of insulin-dependent diabetes mellitus in NOD mice. Circ Shock 43:198-201
Tisch, R; Yang, X D; Liblau, R S et al. (1994) Administering glutamic acid decarboxylase to NOD mice prevents diabetes. J Autoimmun 7:845-50

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