Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI025904-09
Application #
2063161
Study Section
Experimental Immunology Study Section (EI)
Project Start
1988-03-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Microbiology/Immun/Virology
Type
Schools of Earth Sciences/Natur
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Torres, Barbara A; Perrin, George Q; Mujtaba, Mustafa G et al. (2002) Superantigen enhancement of specific immunity: antibody production and signaling pathways. J Immunol 169:2907-14
Soos, Jeanne M; Mujtaba, Mustafa G; Schiffenbauer, Joel et al. (2002) Intramolecular epitope spreading induced by staphylococcal enterotoxin superantigen reactivation of experimental allergic encephalomyelitis. J Neuroimmunol 123:30-4
Subramaniam, P S; Green, M M; Larkin 3rd, J et al. (2001) Nuclear translocation of IFN-gamma is an intrinsic requirement for its biologic activity and can be driven by a heterologous nuclear localization sequence. J Interferon Cytokine Res 21:951-9
Kominsky, S L; Torres, B A; Hobeika, A C et al. (2001) Superantigen enhanced protection against a weak tumor-specific melanoma antigen: implications for prophylactic vaccination against cancer. Int J Cancer 94:834-41
Torres, B A; Kominsky, S; Perrin, G Q et al. (2001) Superantigens: the good, the bad, and the ugly. Exp Biol Med (Maywood) 226:164-76
Mujtaba, M G; Villarete, L; Johnson, H M (1999) IFN-tau inhibits IgE production in a murine model of allergy and in an IgE-producing human myeloma cell line. J Allergy Clin Immunol 104:1037-44
Perrin, G Q; Johnson, H M; Subramaniam, P S (1999) Mechanism of interleukin-10 inhibition of T-helper cell activation by superantigen at the level of the cell cycle. Blood 93:208-16
Mujtaba, M G; Streit, W J; Johnson, H M (1998) IFN-tau suppresses both the autoreactive humoral and cellular immune responses and induces stable remission in mice with chronic experimental allergic encephalomyelitis. Cell Immunol 186:94-102
Torres, B A; Johnson, H M (1998) Modulation of disease by superantigens. Curr Opin Immunol 10:465-70
Torres, B A; Tanabe, T; Subramaniam, P S et al. (1998) Mechanism of HIV pathogenesis: role of superantigens in disease. Alcohol Clin Exp Res 22:188S-192S

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