Magnetoencephalography (MEG) is an important functional neuroimaging technique that provides an excellent combination of high spatial and temporal resolution. At present, MEG scanners are handicapped by cost and complexity imposed by cryogenically cooled superconducting sensor technology. In our recently completed Phase II project, we developed new noncryogenic optical sensors that are suitable replacements for superconducting sensors in MEG systems. In this project, using our newly developed sensors, we will build a low cost, room temperature, ?wearable? MEG system with resolution exceeding current gold standards. The system developed in this project will be an advanced commercialization ready prototype suitable for neuroscience research applications.

Public Health Relevance

National Institute of Mental Health estimates from 2016 suggests around 44.7 million people over the age of 18 suffer from mental illness. The technology development in this project will lead to a step-change in our ability to understand how the brain works, diagnose, and treat mental disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44MH110288-03
Application #
10080331
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Rao, Vasudev
Project Start
2016-04-01
Project End
2023-06-30
Budget Start
2020-07-03
Budget End
2021-06-30
Support Year
3
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Quspin
Department
Type
DUNS #
965475895
City
Louisville
State
CO
Country
United States
Zip Code
80027
Holmes, Niall; Leggett, James; Boto, Elena et al. (2018) A bi-planar coil system for nulling background magnetic fields in scalp mounted magnetoencephalography. Neuroimage 181:760-774
Boto, Elena; Holmes, Niall; Leggett, James et al. (2018) Moving magnetoencephalography towards real-world applications with a wearable system. Nature 555:657-661