Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Minority Biomedical Research Support Thematic Project Grants (S11)
Project #
5S11RR002660-04
Application #
3564543
Study Section
General Research Support Program Advisory Committee (GRS)
Project Start
1985-09-30
Project End
1989-09-29
Budget Start
1988-09-30
Budget End
1989-09-29
Support Year
4
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Florida Agricultural and Mechanical University
Department
Type
DUNS #
City
Tallahassee
State
FL
Country
United States
Zip Code
32307

  Publications

Khan, M Omar F; Lee, Henry J (2008) Synthesis and pharmacology of anti-inflammatory steroidal antedrugs. Chem Rev 108:5131-45
Omar, M; Khan, F; Park, Kwan K et al. (2007) New steroidal anti-inflammatory antedrugs: 21-thioalkylether derivatives of methyl 16-prednisolone carboxylates. Med Chem 3:572-5
Park, Kwan-Kyun; Ko, Dong-Hoon; You, Zhengqing et al. (2006) Synthesis and pharmacological evaluations of new steroidal anti-inflammatory antedrugs: 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-3,20-dioxo-pregna-1,4-diene-16alpha-carboxylate (FP16CM) and its derivatives. Steroids 71:83-9
You, Zhengqing; Lee, Henry Young (2006) New AZT conjugates as potent anti-HIV agents. Nucleosides Nucleotides Nucleic Acids 25:37-54
Park, Kwan-K; Ko, Dong-H; You, Z et al. (2006) In vitro anti-inflammatory activities of new steroidal antedrugs: [16alpha,17alpha-d] Isoxazoline and [16alpha,17alpha-d]-3'-hydroxy-iminoformyl isoxazoline derivatives of prednisolone and 9alpha-fluoroprednisolone. Steroids 71:183-8
Khan, M Omar F; Park, Kwan K; Lee, Henry J (2005) Antedrugs: an approach to safer drugs. Curr Med Chem 12:2227-39
Park, Kwan-kyun; Ko, Dong-hoon; You, Zhengqing et al. (2004) Chirality effect of C-20 on metabolism of methyl 11beta,17alpha,20-trihydroxy-3-oxo-1,4-pregnadien-21-oate derivatives. Steroids 69:87-91
You, Zhengqing; Mian, A Moshin; Agarwal, Ram P et al. (2003) Synthesis, anti-HIV, and cytotoxic activity of new AZT conjugates of steroid acids. Nucleosides Nucleotides Nucleic Acids 22:2049-60
Park, Kwan-Kyun; Ko, Dong-Hoon; You, Zhengqing et al. (2003) Metabolism of steroidal anti-inflammatory antedrugs in vitro: methyl 3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-16alpha-carboxylate; its 9alpha-fluorinated, and their 21-O-acyl derivatives. Steroids 68:315-9
Ko, Dong-Hoon; Heiman, Ann S; Hudson, Charles E et al. (2002) New steroidal antiinflammatory antedrugs: Methyl 3,20-dioxo-9 alpha-fluoro-11 beta,17 alpha,21-trihydroxy-1,4-pregnadiene-16 alpha-carboxylate and its 21-O-acyl derivatives. Steroids 67:211-9

Showing the most recent 10 out of 26 publications