This is a new application for a T32 predoctoral and postdoctoral training program to provide interdisciplinary research training for nurse scientists pursuing careers focused on populations with multiple chronic conditions. The co-existence of multiple chronic conditions confers a compounding burden on overall health status, functional ability, and quality of life. The next generation of nurse scientists needs to be equipped with the knowledge and skills required to tackle the study of the complex phenomena associated with research addressing multiple chronic conditions across the translational continuum. The use of conceptual models and methods from several fields of study is needed, as well as the integration of multiple interdisciplinary perspectives, methodologies, and levels of analyses. The use of new analytic methods is needed to examine mechanisms and interactions of multiple chronic conditions and treatment effects, the clustering of morbidities, and the influence of known confounders. A cadre of expertly trained researchers who can conduct research among and within populations with multiple chronic conditions will assist to reduce the health disparitie among vulnerable groups in our society known to have high multiple morbidity, including those of minority racial/ethnicity, the very young and the very old and those with disabilities. To enhance the cultural diversity of the research workforce, we are collaborating with two minority- serving institutions: Florida Agricultural and Mechanical (A&M) School of Nursing, a historically black university, and Lehman College and Graduate School at City University of New York (CUNY), a Hispanic- serving institution. We will recruit minority trainees from Florida A&M and Lehman at CUNY into our fast-track BSN to PhD program and postdoctoral training program. Building on the success of our past and existing T32, this NRSA will support 8 predoctoral and 9 postdoctoral trainees over 5 years. We have enhanced our existing program to include an emphasis on research training that is more interdisciplinary, encourages the use of NIH intramural research opportunities for early career investigators, requires an introduction to genetics and gene-environment interactions as biological- social context for understanding multiple chronic conditions, and provides advanced training in statistical methods appropriate for longitudinal, multi-level, or lagged effects analyses.

Public Health Relevance

For over 75 million people in the U.S., the co-existence of two or more chronic conditions confers a compounding burden on overall health, functional ability, and quality of life. A cadre of expertly trained nurse scientists, who can conduct research among and within populations with multiple chronic conditions, is crucial to reduce the disparities in health and quality of life that this population experience. The proposed training program will support 8 predoctoral and 9 postdoctoral trainees over 5 years.

Agency
National Institute of Health (NIH)
Institute
National Institute of Nursing Research (NINR)
Type
Institutional National Research Service Award (T32)
Project #
5T32NR015433-05
Application #
9728058
Study Section
Special Emphasis Panel (ZNR1)
Program Officer
Banks, David
Project Start
2015-07-01
Project End
2020-06-30
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
5
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Type
Schools of Nursing
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
O'Connell, Grant C; Chang, Julia H C (2018) Analysis of Early Stroke-induced Changes in Circulating Leukocyte Counts using Transcriptomic Deconvolution. Transl Neurosci 9:161-166
Heerman, William J; Berge, Jerica M; Barkin, Shari L (2018) Mentoring of Early-Stage Investigators When Funding Is Tight: The Childhood Obesity Prevention and Treatment Research Experience. JAMA Pediatr 172:4-6
Hardin, Heather K; McCarthy, Valerie Lander; Speck, Barbara J et al. (2018) Diminished Trust of Healthcare Providers, Risky Lifestyle Behaviors, and Low Use of Health Services: A Descriptive Study of Rural Adolescents. J Sch Nurs 34:458-467
Irani, Elliane; Hirschman, Karen B; Cacchione, Pamela Z et al. (2018) Home health nurse decision-making regarding visit intensity planning for newly admitted patients: a qualitative descriptive study. Home Health Care Serv Q 37:211-231
Moore, Scott Emory; Ulbrich, Holley H; Hepburn, Kenneth et al. (2018) Behavioral Economics: A New Lens for Understanding Genomic Decision Making. J Nurs Scholarsh 50:241-248
Webel, Allison R; Moore, Shirley M; Longenecker, Chris T et al. (2018) Randomized Controlled Trial of the SystemCHANGE Intervention on Behaviors Related to Cardiovascular Risk in HIV+ Adults. J Acquir Immune Defic Syndr 78:23-33
Gallinaro, Alessandra; Borghi, Martina; Bona, Roberta et al. (2018) Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens. Front Immunol 9:171
Weber, Ashley; Harrison, Tondi M; Sinnott, Loraine et al. (2018) Associations Between Nurse-Guided Variables and Plasma Oxytocin Trajectories in Premature Infants During Initial Hospitalization. Adv Neonatal Care 18:E12-E23
Weber, Ashley M; Harrison, Tondi M; Steward, Deborah K (2018) Expanding Regulation Theory With Oxytocin: A Psychoneurobiological Model for Infant Development. Nurs Res 67:133-145
Wang, Zhao; Huang, Bing; Thomas, Milton et al. (2018) Detailed mapping of the linear B Cell epitopes of the hemagglutinin (HA) protein of swine influenza virus. Virology 522:131-137

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