Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01AI031921-06
Application #
2066851
Study Section
Special Emphasis Panel (SRC (86))
Project Start
1991-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Immune Disease Institute, Inc.
Department
Type
DUNS #
115524410
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Casasnovas, J M; Stehle, T; Liu, J H et al. (1998) A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1. Proc Natl Acad Sci U S A 95:4134-9
Wang, J; Springer, T A (1998) Structural specializations of immunoglobulin superfamily members for adhesion to integrins and viruses. Immunol Rev 163:197-215
Casasnovas, J M; Bickford, J K; Springer, T A (1998) The domain structure of ICAM-1 and the kinetics of binding to rhinovirus. J Virol 72:6244-6
Springer, T A (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301-14
Casasnovas, J M; Springer, T A (1994) Pathway of rhinovirus disruption by soluble intercellular adhesion molecule 1 (ICAM-1): an intermediate in which ICAM-1 is bound and RNA is released. J Virol 68:5882-9
Martin, S; Casasnovas, J M; Staunton, D E et al. (1993) Efficient neutralization and disruption of rhinovirus by chimeric ICAM-1/immunoglobulin molecules. J Virol 67:3561-8
Martin, S; Casanovas, J M; Staunton, D E et al. (1993) [Successful prevention of rhinovirus infections with chimeric ICAM-1 immunoglobulin in vitro] Med Klin (Munich) 88:193-7
Martin, S; Martin, A; Staunton, D E et al. (1993) Functional studies of truncated soluble intercellular adhesion molecule 1 expressed in Escherichia coli. Antimicrob Agents Chemother 37:1278-84
Staunton, D E; Gaur, A; Chan, P Y et al. (1992) Internalization of a major group human rhinovirus does not require cytoplasmic or transmembrane domains of ICAM-1. J Immunol 148:3271-4