Abstract

This application, in response to RFA TR-12-006: """"""""Institutional Clinical and Translational Science Award (U54)"""""""", requests support for the University of Utah's Center for Clinical and Translational Science (CCTS). Our CCTS is built upon the UU's historic strengths in genetics and bioinformatics. Our vision for the next five years is to maintain and leverage the service cores of the CCTS and use that infrastructure as a springboard to launch new programs. With implementation of this vision we will fulfill the Aims of the CTSA described in the FOA by maintaining a home for translational research to: (1) Increase the quality, quantity, safety, efficiency, and impact of translational research for all conditions;(2) Provide resources and services to support and speed the planning and implementation of clinical and translational research across the entire range of research and communities;(3) Train, mentor, and support the next generation of translational investigators through the stage of becoming principal investigators and productive faculty members;(4) Maintain a governance structure that represents the full spectrum of translational science and all of its stakeholders to effectively fulfill the Aims;(5) Engage in a process of continuous evaluation, improvement, and innovation in all of these areas. The mission of the UU CCTS will be to provide support for all aspects of translational research. Even support that can be characterized as """"""""service"""""""" will be used to inform innovation and catalyze new thinking. In addition, we will direct new resources toward providing special expertise to the CTSA consortium in specific areas, namely: Human genetics;genotype/phenotype correlation;health services research including comparative effectiveness;medical device innovation, and;taking the electronic medical record to the next level as a tool for medical care and medical research. We will continue to perform research aimed at re-engineering the process of translational investigation.

Public Health Relevance

; Providing resources and services to support and speed the planning and implementation of clinical and translational research across the entire range of research and communities.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Specialized Center Cooperative Agreement (UL1)
Project #
5UL1TR001067-02
Application #
8743325
Study Section
Special Emphasis Panel (ZAI1-PTM-C (S1))
Program Officer
Brazhnik, Olga
Project Start
2013-09-26
Project End
2018-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
2
Fiscal Year
2014
Total Cost
$4,099,530
Indirect Cost
$1,316,210

  Institution

Name
University of Utah
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Albano, Juan M R; Mussini, Nahuel; Toriano, Roxana et al. (2018) Calcium interactions with Cx26 hemmichannel: Spatial association between MD simulations biding sites and variant pathogenicity. Comput Biol Chem 77:331-342
Murtaugh, Maureen A; Beasley, Jeannette M; Appel, Lawrence J et al. (2018) Relationship of Sodium Intake and Blood Pressure Varies With Energy Intake: Secondary Analysis of the DASH (Dietary Approaches to Stop Hypertension)-Sodium Trial. Hypertension 71:858-865
Kapron, Ashley L; Karns, Michael R; Aoki, Stephen K et al. (2018) Patient-Specific Parameters Associated With Traction in Primary and Revision Hip Arthroscopic Surgery. Orthop J Sports Med 6:2325967118807707
Reynolds, Megan M; Avendano, Mauricio (2018) Social Policy Expenditures and Life Expectancy in High-Income Countries. Am J Prev Med 54:72-79
Ghaffarian, Amir A; Al-Dulaimi, Ragheed; Kraiss, Larry W et al. (2018) Clinical effectiveness of open thrombectomy for thrombosed autogenous arteriovenous fistulas and grafts. J Vasc Surg 68:189-196
Alderden, Jenny; Zhao, Yunchuan Lucy; Zhang, Yingying et al. (2018) Outcomes Associated With Stage 1 Pressure Injuries: A Retrospective Cohort Study. Am J Crit Care 27:471-476
Reidy, Paul T; McKenzie, Alec I; Mahmassani, Ziad et al. (2018) Skeletal muscle ceramides and relationship with insulin sensitivity after 2 weeks of simulated sedentary behaviour and recovery in healthy older adults. J Physiol 596:5217-5236
Lamb, Brandy; Johnson, Erin; Francis, Leslie et al. (2018) Pre-implantation genetic testing: decisional factors to accept or decline among in vitro fertilization patients. J Assist Reprod Genet 35:1605-1612
Kazmers, Nikolas H; Judson, Christopher H; Presson, Angela P et al. (2018) Evaluation of Factors Driving Cost Variation for Distal Radius Fracture Open Reduction Internal Fixation. J Hand Surg Am 43:606-614.e1
Wu, Yelena P; Linder, Lauri A; Kanokvimankul, Patsaporn et al. (2018) Use of a Smartphone Application for Prompting Oral Medication Adherence Among Adolescents and Young Adults With Cancer?. Oncol Nurs Forum 45:69-76

Showing the most recent 10 out of 290 publications