Abstract

The Oswaldo Cruz Foundation (FIOCRUZ) Therapeutic and Prevention HIV/AIDS Clinical Trials Unit (FioTrials), is a multidisciplinary, integrated research consortium based in Rio de Janeiro, Brazil with two clinical research sites (CRS) located at the Institute de Pesquisa Clinica Evandro Chagas (IPEC CRS) and Hospital Geral de Nova Iguagu (HGNI CRS). Both sites offer routine clinical care for both """"""""at-risk"""""""" and HIV-infected persons and cater to the needs of certain disenfranchised populations, which include individuals who may be racial minorities, women, poverty stricken, uneducated, and/or substance abusers. As a whole, the FioTrials unit has unique strengths to offer the ACTG and HPTN networks, as an established and integrated unit leadership who is partnered with FIOCRUZ, a supportive research-driven institution, a participant population that complements the scientific agendas of both networks, and researchers with significant experience in the development of HIV/AIDS prevention and treatment strategies. ADMINISTRATIVE COMPONENT:

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project with Complex Structure Cooperative Agreement (UM1)
Project #
4UM1AI069476-06
Application #
8415479
Study Section
Special Emphasis Panel (ZAI1-BLG-A (M2))
Program Officer
Castillo, Blanca E
Project Start
2008-01-15
Project End
2013-12-09
Budget Start
2013-01-01
Budget End
2013-12-09
Support Year
6
Fiscal Year
2013
Total Cost
$3,247,921
Indirect Cost
$22,748

  Institution

Name
Fundacao Oswaldo Cruz
Department
Type
DUNS #
899294177
City
Rio de Janeiro
State
Country
Brazil
Zip Code
21040--360

  Publications

Bakal, David R; Coelho, Lara E; Luz, Paula M et al. (2018) Obesity following ART initiation is common and influenced by both traditional and HIV-/ART-specific risk factors. J Antimicrob Chemother 73:2177-2185
De Boni, Raquel B; Peratikos, Meridith B; Shepherd, Bryan E et al. (2018) Is substance use associated with HIV cascade outcomes in Latin America? PLoS One 13:e0194228
Adachi, Kristina; Xu, Jiahong; Ank, Bonnie et al. (2018) Congenital CMV and HIV Perinatal Transmission. Pediatr Infect Dis J :
Ngongondo, McNeil; Miyahara, Sachiko; Hughes, Michael D et al. (2018) Hepatotoxicity During Isoniazid Preventive Therapy and Antiretroviral Therapy in People Living With HIV With Severe Immunosuppression: A Secondary Analysis of a Multi-Country Open-Label Randomized Controlled Clinical Trial. J Acquir Immune Defic Syndr 78:54-61
Torres, Thiago S; Harrison, Linda J; La Rosa, Alberto M et al. (2018) Quality of life improvement in resource-limited settings after one year of second-line antiretroviral therapy use among adult men and women. AIDS 32:583-593
Caniglia, Ellen C; Phillips, Andrew; Porter, Kholoud et al. (2018) Commonly Prescribed Antiretroviral Therapy Regimens and Incidence of AIDS-Defining Neurological Conditions. J Acquir Immune Defic Syndr 77:102-109
Luz, Paula M; Benzaken, Adele; Alencar, Tatianna M de et al. (2018) PrEP adopted by the brazilian national health system: What is the size of the demand? Medicine (Baltimore) 97:S75-S77
Poynard, Thierry; Munteanu, Mona; Charlotte, Frederic et al. (2018) Impact of steatosis and inflammation definitions on the performance of NASH tests. Eur J Gastroenterol Hepatol 30:384-391
De Boni, Raquel B; Lentini, Nena; Santelli, Ana Cfs et al. (2018) Self-testing, communication and information technology to promote HIV diagnosis among young gay and other men who have sex with men (MSM) in Brazil. J Int AIDS Soc 21 Suppl 5:e25116
Carriquiry, Gabriela; Giganti, Mark J; Castilho, Jessica L et al. (2018) Virologic failure and mortality in older ART initiators in a multisite Latin American and Caribbean Cohort. J Int AIDS Soc 21:e25088

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