During the present report period, antitumor and anti-HIV bioassay-guided fractionation has led to a variety of structurally and biologically intriguing new compounds from marine animals and terrestrial plants. Efforts have been focused on the following: cytotoxic saponins from legumes, isolation of cytotoxic and anti-HIV sponge proteins, cytotoxic sesquiterpenes from an alga, and dereplication of phorbol esters from extracts from the family Euphorbiaceae.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Intramural Research (Z01)
Project #
1Z01CM007329-03
Application #
3752436
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Division of Cancer Treatment
Department
Type
DUNS #
City
State
Country
United States
Zip Code