To date this study has shown that children exposed to large quantities of alcohol in utero have abnormal nerve conduction velocities despite not having classic fetal alcohol syndrome. The study has also shown that the risk of ophthalmologic abnormalities is limited to those who have fetal alcohol syndrome;other heavily exposed children did not have a excess of eye defects. The study has completed the classification of all exposed subjects into categories that define the adverse effects that they have experienced. Subjects can now be analyzed based on the categories of classic fetal alcohol syndrome (FAS) or fetal alcohol spectrum disorder or alcohol related neurological defects. This will make it possible to link outcomes in exposed children to data on alcohol exposure collected during their prenatal life.
| Cornman-Homonoff, Joshua; Kuehn, Devon; Aros, Sofía et al. (2012) Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery. J Matern Fetal Neonatal Med 25:860-3 |
| Kuehn, Devon; Aros, Sofia; Cassorla, Fernando et al. (2012) A prospective cohort study of the prevalence of growth, facial, and central nervous system abnormalities in children with heavy prenatal alcohol exposure. Alcohol Clin Exp Res 36:1811-9 |
| Aros, Sofia; Mills, James L; Iniguez, German et al. (2011) Effects of prenatal ethanol exposure on postnatal growth and the insulin-like growth factor axis. Horm Res Paediatr 75:166-73 |
| Flanigan, Elizabeth Y; Aros, Sofia; Bueno, Maria Ferraz et al. (2008) Eye malformations in children with heavy alcohol exposure in utero. J Pediatr 153:391-5 |
| Signore, Caroline; Aros, Sofia; Morrow, Jason D et al. (2008) Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking >or =48 g of alcohol per day. Alcohol Clin Exp Res 32:1893-8 |
