Our study design enabled us to identify and follow 96 women consuming at least 4 drinks/day during pregnancy. In these women with heavy prenatal alcohol use, there were three stillbirths and one preterm delivery;98 matched nondrinking women had no stillbirths and two preterm births. Preterm rates did not differ significantly. The stillbirth rate was higher in the exposed group (p = 0.06). Additional investigation showed the stillbirth rate in the exposed population (3.1%) was significantly higher (p = 0.019) than the reported Chilean population rate (0.45%). Our data suggest that heavy alcohol consumption may increase the risk for stillbirth but not preterm delivery. Analysis is now complete and a report has been prepared describing the outcomes of the exposed children based on the amount and pattern of maternal alcohol consumption during pregnancy. The data will be reported soon.
| Cornman-Homonoff, Joshua; Kuehn, Devon; Aros, Sofía et al. (2012) Heavy prenatal alcohol exposure and risk of stillbirth and preterm delivery. J Matern Fetal Neonatal Med 25:860-3 |
| Kuehn, Devon; Aros, Sofia; Cassorla, Fernando et al. (2012) A prospective cohort study of the prevalence of growth, facial, and central nervous system abnormalities in children with heavy prenatal alcohol exposure. Alcohol Clin Exp Res 36:1811-9 |
| Aros, Sofia; Mills, James L; Iniguez, German et al. (2011) Effects of prenatal ethanol exposure on postnatal growth and the insulin-like growth factor axis. Horm Res Paediatr 75:166-73 |
| Flanigan, Elizabeth Y; Aros, Sofia; Bueno, Maria Ferraz et al. (2008) Eye malformations in children with heavy alcohol exposure in utero. J Pediatr 153:391-5 |
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