The current influenza pandemic has made evident the gaps in knowledge about and response capacity for emerging infectious diseases. In the first stage of our award, "Peru Infectious Diseases Epidemiology Research Training Consortium", the NMRCD-UPCH-JHBSPH-USUHS consortium has contributed to building sustainable research capacity in Peru. Two Masters'graduates and one PhD candidate returned to Peru and are studying key epidemiologic and ecologic aspects of pandemic and seasonal influenza, and three trainees are finishing coursework. Also, we established a nearly self-sustainable, tuition-funded Epidemiology Masters in Peru which is taught by 30+ Peruvian/foreign PhDs and PhD candidates, many funded by NIH research and training grants. We have trained 43 students in two successive cohorts, and students from the first cohort have published 13 papers in peer-reviewed journals within a year of training. Important progress has been made, but substantial efforts are still needed. The renewal proposal will consolidate our work by 1) supporting degree completion of current trainees and nurturing return to Peru, and 2) complete establishment a world-class and self-sustainable Epidemiology Masters program in Peru, 3) broadening training options in Peru via a Summer Institute of Epidemiological Research, 4) build capacity in Andean Ministries of Health through 4 ear-marked Masters scholarships, 5) formally adding the CDC and Universidad San Marcos as key partners. This second award will support 2 PhD students, 20 Masters Graduates and 21 students of certificate programs, 30% of them trained in the US. The consortium will continue to use the proven, successful approach of combining coursework, applied research, and mentored achievement-driven progression and using all training programs available. Trainees will prepare a protocol, obtain IRB approval, conduct research, submit a manuscript, and apply for external funding, completing the research cycle. Training will take place in a superb environment of the consortium which includes numerous successful NIH collaborations, extensive multi-year research, a large pool of highly trained local and foreign mentors, sophisticated laboratories, and diverse field and clinical sites. Public Health Relevance: We built sustainable research capacity in our first award by creating a high-quality Epidemiology Masters Program in Peru and combining with advanced degree training in the US. The first trainees are conducting important studies on seasonal and pandemic influenza and published important studies rapidly. The renewal proposal should consolidate these efforts with further local training in Peru, reaching out to Ministries of Health in Andean countries and complete establishing self-sustainable advanced programs in Peru

Public Health Relevance

We built sustainable research capacity in our first award by creating a high-quality Epidemiology Masters Program in Peru and combining with advanced degree training in the US. The first trainees are conducting important studies on seasonal and pandemic influenza and published important studies rapidly. The renewal proposal should consolidate these efforts with further local training in Peru, reaching out to Ministries of Health in Andean countries and complete establishing self-sustainable advanced programs in Peru

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW007393-09
Application #
8531190
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (50))
Program Officer
Sina, Barbara J
Project Start
2005-09-01
Project End
2015-05-31
Budget Start
2013-06-01
Budget End
2014-05-31
Support Year
9
Fiscal Year
2013
Total Cost
$174,800
Indirect Cost
Name
Naval Medical Research Unit Number Six
Department
Type
DUNS #
078286517
City
Silver Spring
State
MD
Country
United States
Zip Code
20910
Moyano, Luz M; Saito, Mayuko; Montano, Silvia M et al. (2014) Neurocysticercosis as a cause of epilepsy and seizures in two community-based studies in a cysticercosis-endemic region in Peru. PLoS Negl Trop Dis 8:e2692
Shender, Lisa A; De Los Santos, Maxy; Montgomery, Joel M et al. (2014) Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru. PLoS One 9:e103358
Garcia, Hector H; Gonzales, Isidro; Lescano, Andres G et al. (2014) Efficacy of combined antiparasitic therapy with praziquantel and albendazole for neurocysticercosis: a double-blind, randomised controlled trial. Lancet Infect Dis 14:687-95
Flores, Elaine C; Carnero, Andres M; Bayer, Angela M (2014) Social capital and chronic post-traumatic stress disorder among survivors of the 2007 earthquake in Pisco, Peru. Soc Sci Med 101:9-17
Oswald, William E; Hunter, Gabrielle C; Kramer, Michael R et al. (2014) Provision of private, piped water and sewerage connections and directly observed handwashing of mothers in a peri-urban community of Lima, Peru. Trop Med Int Health 19:388-97
Quispe, Antonio M; Pozo, Edwar; Guerrero, Edith et al. (2014) Plasmodium vivax hospitalizations in a monoendemic malaria region: severe vivax malaria? Am J Trop Med Hyg 91:11-7
Garcia, Hector H; Gonzales, Isidro; Lescano, Andres G et al. (2014) Enhanced steroid dosing reduces seizures during antiparasitic treatment for cysticercosis and early after. Epilepsia 55:1452-9
Durand, Salomón; Cabezas, Cesar; Lescano, Andres G et al. (2014) Efficacy of three different regimens of primaquine for the prevention of relapses of Plasmodium vivax malaria in the Amazon Basin of Peru. Am J Trop Med Hyg 91:18-26
Maguina, Jorge L; Konda, Kelika A; Leon, Segundo R et al. (2013) Relationship between alcohol consumption prior to sex, unprotected sex and prevalence of STI/HIV among socially marginalized men in three coastal cities of Peru. AIDS Behav 17:1724-33
Tsukayama, Pablo; Nunez, Jorge H; De Los Santos, Maxy et al. (2013) A FRET-based real-time PCR assay to identify the main causal agents of New World tegumentary leishmaniasis. PLoS Negl Trop Dis 7:e1956

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