This proposed training program is a renewal of our current 'Tanzania Infectious Disease Research Training Program' that is focused on pediatric infectious diseases in Tanzania. Over the past twenty years, the Harvard School of Public Health (HSPH) and Muhimbili University Health and Allied Sciences (MUHAS) Partnership has contributed significantly to training and research capacity in Tanzania. The goal of this training program is to develop skilled researchers in Tanzania in the area of pediatric infectious diseases and nutrition. We propose to provide research training to public health leaders in epidemiological, operations and health services, laboratory, and clinical areas, with a focus on childhood diarrheal diseases and acute respiratory infections. This program will harness scientific knowledge and skills to enhance prevention, treatment and control of pediatric infectious diseases causing major morbidity and mortality in Tanzania. The program will be structured to provide an appropriate balance of short-, medium-and long-term training opportunities in Boston and Tanzania for participants from Tanzania. The principle strategies are: year-long postdoctoral training, short-term postdoctoral training, intensive short courses, and symposia. In total the program will train 5 year-long postdoctoral fellows in Boston, 15 short-term postdoctoral fellows at HSPH with continued mentoring over the subsequent 2 years in Dar es Salaam, and provide short course instruction to 300 individuals. Additionally hundreds will be reached through the annual symposia. Trainees will benefit from exposure to the ongoing collaboration with Tanzanian institutions including epidemiological and laboratory studies, clinical trials, and operations research programs. These activities will provide unique training opportunities for study design and implementation, data analysis and career advancement. Research funds will be awarded to returning postdoctoral trainees, in order to facilitate integration into the research setting in Tanzania. Deliverables include manuscript development and the development of sound research proposals. Research findings will be disseminated to health care providers, policy makers, students and faculty at academic institutions, and the broader scientific community via an annual symposium in Dar es Salaam. Harvard and Muhimbili faculty with extensive experience in pediatric infectious disease and nutrition research will mentor trainees throughout the program. A Training Advisory Group will evaluate ongoing research progress, and an Executive Committee will be charged with program oversight. The renewal submission accounts for lessons learned from the current training program, including the need for biostatistical support at MUHAS to advance efforts by trainees on their data analysis, and more instruction and closer mentoring in manuscript development. The training program will develop a cadre of skilled public health professionals and facilitate sustainable capacity in pediatric infectious disease and nutrition research in Tanzania. The training program has been developed, and will be implemented, in collaboration with Tanzanian partners.

Public Health Relevance

Of the 7.6 million deaths in children younger than 5 years in 2010, 64% were attributable to infectious causes [1] and malnutrition is the underlying contributing factor in over one third of all child deaths. The Tanzania Infectious Disease Research Training Program, proposed by a the Harvard School of Public Health and Muhimbili University of Health and Allied Science, will harness scientific knowledge and skills to enhance prevention, treatment and control of pediatric infectious diseases causing major morbidity and mortality in Tanzania and develop stronger capacity related to nutrition given its central role in the incidence and severity of infection.

Agency
National Institute of Health (NIH)
Institute
Fogarty International Center (FIC)
Type
International Research Training Grants (D43)
Project #
5D43TW007886-09
Application #
9230457
Study Section
Special Emphasis Panel (ZRG1-IDM-U (56)R)
Program Officer
Sina, Barbara J
Project Start
2007-09-11
Project End
2018-12-31
Budget Start
2017-01-01
Budget End
2017-12-31
Support Year
9
Fiscal Year
2017
Total Cost
$221,865
Indirect Cost
$9,564
Name
Harvard University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02115
Bhimji, Khadija Murtaza; Naburi, Helga; Aboud, Said et al. (2018) Vitamin D Status and Associated Factors in Neonates in a Resource Constrained Setting. Int J Pediatr 2018:9614975
Mosha, Dominic; Liu, Enju; Hertzmark, Ellen et al. (2017) Dietary iron and calcium intakes during pregnancy are associated with lower risk of prematurity, stillbirth and neonatal mortality among women in Tanzania. Public Health Nutr 20:678-686
Kamenju, Pili; Liu, Enju; Hertzmark, Ellen et al. (2017) Complementary Feeding and Diarrhea and Respiratory Infection Among HIV-Exposed Tanzanian Infants. J Acquir Immune Defic Syndr 74:265-272
Walli, Nahida Z; Munubhi, Emmanuel K; Aboud, Said et al. (2017) Vitamin D Levels in Malnourished Children under 5 Years in a Tertiary Care Center at Muhimbili National Hospital, Dar es Salaam, Tanzania-A Cross-sectional Study. J Trop Pediatr 63:203-209
Kamenju, Pili; Liu, Enju; Hertzmark, Ellen et al. (2017) Nutritional status and complementary feeding among HIV-exposed infants: a prospective cohort study. Matern Child Nutr 13:
Chirande, Lulu; Charwe, Deborah; Mbwana, Hadijah et al. (2015) Determinants of stunting and severe stunting among under-fives in Tanzania: evidence from the 2010 cross-sectional household survey. BMC Pediatr 15:165