Human Endogenous Retrovirus K (HERV-K) has been associated with several severe human diseases including, but not limited to, auto-immune diseases, HIV-1 infection, and multiple malignancies. The goal of this project is to better understand the viral lifecycle of the HERV-K family, both in its historical and contemporary context.
|Contreras-Galindo, Rafael; Kaplan, Mark H; Dube, Derek et al. (2015) Human Endogenous Retrovirus Type K (HERV-K) Particles Package and Transmit HERV-K-Related Sequences. J Virol 89:7187-201|
|Zahn, Joseph; Kaplan, Mark H; Fischer, Sabrina et al. (2015) Expansion of a novel endogenous retrovirus throughout the pericentromeres of modern humans. Genome Biol 16:74|
|Dube, Derek; Contreras-Galindo, Rafael; He, Shirley et al. (2014) Genomic flexibility of human endogenous retrovirus type K. J Virol 88:9673-82|